Anti-RPS6KA6 Antibody (CAB14876)
- SKU:
- CAB14876
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RPS6KA6 Antibody |
| 抗体コード: | CAB14876 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 646-745 of human RPS6KA6 (NP_055311.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 646-745 of human RPS6KA6 (NP_055311.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | GGNW DNIS DGAK DLLS HMLH MDPH QRYT AEQI LKHS WITH RDQL PNDQ PKRN DVSH VVKG AMVA TYSA LTHK TFQP VLEP VAAS SLAQ RRSM KKRT STGL |
| 遺伝子ID: | 27330 |
| Uniprot: | Q9UK32 |
| セルラーロケーション: | Cytoplasm, Nucleus, cytosol |
| 計算された分子量: | 83kDa/84kDa |
| 観察された分子量: | 84kDa |
| 同義語: | RPS6KA6, PP90RSK4, RSK-4, RSK4, S6K-alpha-6, p90RSK6 |
| バックグラウンド: | This gene encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways. |
| UniProt Protein Function: | RSK4: an AGC kinase of the RSK family. Phosphorylates a wide range of substrates including ribosomal protein S6. Implicated in the activation of the mitogen- activated kinase cascade. May play a role in normal neuronal development. |
| UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Kinase, protein; Protein kinase, AGC; AGC group; RSK family; RSK subfamily Chromosomal Location of Human Ortholog: Xq21 Cellular Component: cytoplasm; cytosol; mitochondrion; nucleolus; nucleoplasm; nucleus Molecular Function:kinase activity; protein kinase activity; protein serine/threonine kinase activity Biological Process: central nervous system development; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; negative regulation of embryonic development; signal transduction |
| NCBI Summary: | This gene encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways. [provided by RefSeq, Jan 2010] |
| UniProt Code: | Q9UK32 |
| NCBI GenInfo Identifier: | 11133131 |
| NCBI Gene ID: | 27330 |
| NCBI Accession: | Q9UK32.1 |
| UniProt Secondary Accession: | Q9UK32,Q6FHX2, Q8WX28, Q9H4S6, B2R854, B7ZL90, |
| UniProt Related Accession: | Q9UK32 |
| Molecular Weight: | 84,093 Da |
| NCBI Full Name: | Ribosomal protein S6 kinase alpha-6 |
| NCBI Synonym Full Names: | ribosomal protein S6 kinase A6 |
| NCBI Official Symbol: | RPS6KA6 |
| NCBI Official Synonym Symbols: | RSK4; PP90RSK4 |
| NCBI Protein Information: | ribosomal protein S6 kinase alpha-6 |
| UniProt Protein Name: | Ribosomal protein S6 kinase alpha-6 |
| UniProt Synonym Protein Names: | 90 kDa ribosomal protein S6 kinase 6; p90-RSK 6; p90RSK6; Ribosomal S6 kinase 4; RSK-4; pp90RSK4 |
| Protein Family: | Ribosomal protein S6 kinase |
| UniProt Gene Name: | RPS6KA6 |
| UniProt Entry Name: | KS6A6_HUMAN |
 | Western blot analysis of extracts of mouse kidney, using RPS6KA6 antibody (CAB14876) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 10s. |
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