Anti-ROM1 Antibody (CAB6970)
- SKU:
- CAB6970
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-ROM1 Antibody |
| 抗体コード: | CAB6970 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 126-263 of human ROM1 (NP_000318.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | MCF7, 293T, Mouse eye |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 126-263 of human ROM1 (NP_000318.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PGSL DEAL EEGL VTAL AHYK DTEV PGHC QAKR LVDE LQLR YHCC GRHG YKDW FGVQ WVSS RYLD PGDR DVAD RIQS NVEG LYLT DGVP FSCC NPHS PRPC LQNR LSDS YAHP LFDP RQPN QNLW AQGC HEVL LEHL QD |
| 遺伝子ID: | 6094 |
| Uniprot: | Q03395 |
| セルラーロケーション: | Membrane, Multi-pass membrane protein |
| 計算された分子量: | 37kDa |
| 観察された分子量: | 74kDa |
| 同義語: | ROM1, ROM, ROSP1, RP7, TSPAN23 |
| バックグラウンド: | This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa. |
| UniProt Protein Function: | ROM1: May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis. Defects in ROM1 may cause retinitis pigmentosa (RP); when associated with defects in PRPH2. Belongs to the PRPH2/ROM1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Cell surface Chromosomal Location of Human Ortholog: 11q13 Cellular Component: integral to plasma membrane Disease: Retinitis Pigmentosa; Retinitis Pigmentosa 7 |
| NCBI Summary: | This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q03395 |
| NCBI GenInfo Identifier: | 4506575 |
| NCBI Gene ID: | 6094 |
| NCBI Accession: | NP_000318.1 |
| UniProt Secondary Accession: | Q03395,B2R978, |
| UniProt Related Accession: | Q03395 |
| Molecular Weight: | 37,205 Da |
| NCBI Full Name: | rod outer segment membrane protein 1 |
| NCBI Synonym Full Names: | retinal outer segment membrane protein 1 |
| NCBI Official Symbol: | ROM1 |
| NCBI Official Synonym Symbols: | ROM; RP7; ROSP1; TSPAN23 |
| NCBI Protein Information: | rod outer segment membrane protein 1 |
| UniProt Protein Name: | Rod outer segment membrane protein 1 |
| UniProt Synonym Protein Names: | Tetraspanin-23; Tspan-23 |
| Protein Family: | Rhomboid-like protease |
| UniProt Gene Name: | ROM1 |
| UniProt Entry Name: | ROM1_HUMAN |
 | Western blot - ROM1 Polyclonal Antibody (CAB6970) |
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