Anti-Rnf170 Antibody (CAB15196)
- SKU:
- CAB15196
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-Rnf170 Antibody |
| 抗体コード: | CAB15196 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of mouse Rnf170 (NP_084241.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse pancreas, Mouse testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of mouse Rnf170 (NP_084241.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MQRY WRFQ DNKI QDIC FGVL GESW IQRP VMAR YYSE GQSL QQDD SFIE GVSD QVLV AVVV SLAL TATL LYAL LRNV QQNI HPEN QELV RVLR EQFQ TEQD VPAP ARQQ FYTE MYCP ICLH QASF PVET NCGH LFCG SCII AYWR YGSW LGAI SCPI CRQT VTLL LTVF GEDD QSQD VIRL RQDV NDYN RRFS GQPR SIME |
| 遺伝子ID: | 77733 |
| Uniprot: | |
| セルラーロケーション: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
| 計算された分子量: | 16kDa/24kDa/28kDa/33kDa |
| 観察された分子量: | 28kDa |
| 同義語: | RNF170, ADSA, SNAX1, Rnf170 |
| バックグラウンド: | This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1, 4, 5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. |
 | Western blot analysis of extracts of various cell lines, using Rnf170 antibody (CAB15196) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |