Anti-RNF170 Antibody (CAB15195)
- SKU:
- CAB15195
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-RNF170 Antibody |
抗体コード: | CAB15195 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 46-120 of human RNF170 (NP_001153696.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse |
ポジティブサンプル: | Mouse thymus, Mouse brain, Mouse pancreas |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 46-120 of human RNF170 (NP_001153696.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | RNVH QNIH PENQ ELVR VLRE QLQT EQDA PAAT RQQF YTDM YCPI CLHQ ASFP VETN CGHL FCGA CIIA YWRY GSW |
遺伝子ID: | 81790 |
Uniprot: | Q96K19 |
セルラーロケーション: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
計算された分子量: | 13kDa/18kDa/20kDa/22kDa/26kDa/29kDa |
観察された分子量: | 30kDa |
同義語: | RNF170, ADSA, SNAX1 |
バックグラウンド: | This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1, 4, 5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. |
NCBI Summary: | This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] |
UniProt Code: | Q96K19 |
NCBI GenInfo Identifier: | 237858654 |
NCBI Gene ID: | 81790 |
NCBI Accession: | NP_112216 |
UniProt Related Accession: | Q96K19 |
Molecular Weight: | 30kDa |
NCBI Full Name: | E3 ubiquitin-protein ligase RNF170 isoform a |
NCBI Synonym Full Names: | ring finger protein 170 |
NCBI Official Symbol: | RNF170 |
NCBI Official Synonym Symbols: | ADSA; SNAX1 |
NCBI Protein Information: | E3 ubiquitin-protein ligase RNF170 |
UniProt Protein Name: | E3 ubiquitin-protein ligase RNF170 |
UniProt Synonym Protein Names: | Putative LAG1-interacting protein; RING finger protein 170 |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | RNF170 |
UniProt Entry Name: | RN170_HUMAN |
View AllClose