Anti-RNF144A Antibody (CAB17597)
- SKU:
- CAB17597
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-RNF144A Antibody |
| 抗体コード: | CAB17597 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 52-179 of human RNF144A (NP_055561.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Rat |
| ポジティブサンプル: | A-431, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 52-179 of human RNF144A (NP_055561.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | ELLI KEGL ETAI SCPD AACP KQGH LQEN EIEC MVAA EIMQ RYKK LQFE REVL FDPC RTWC PAST CQAV CQLQ DVGL QTPQ PVQC KACR MEFC STCK ASWH PGQG CPET MPIT FLPG ETSA AFKM EEDD |
| 遺伝子ID: | 9781 |
| Uniprot: | P50876 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 38kDa |
 | Western blot - RNF144A Polyclonal Antibody (CAB17597) |
| 同義語: | RNF144, UBCE7IP4, hUIP4, RNF144A |
| バックグラウンド: | This gene encodes a member of a family of RING finger domain-containing E3 ubiquitin ligases that also includes parkin and parc. The expression of this gene is induced by DNA damage. The encoded protein interacts with the cytoplasmic DNA-dependent protein kinase, catalytic subunit (DNA-PKcs) and promotes its degradation through ubiquitination. The orthologous mouse protein has been shown to interact with a ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Mar 2017] |
| UniProt Protein Function: | RNF144A: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Belongs to the RBR family. RNF144 subfamily. |
| UniProt Protein Details: | Protein type:Ubiquitin ligase; Ligase; Membrane protein, integral; EC 6.3.2.-; EC 6.3.2.19; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 2p25.2 Cellular Component: Golgi apparatus; ubiquitin ligase complex Molecular Function:ubiquitin conjugating enzyme binding Biological Process: positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process |
| NCBI Summary: | The protein encoded by this protein contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The mouse counterpart of this protein has been shown to interact with Ube2l3/UbcM4, which is an ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P50876 |
| NCBI GenInfo Identifier: | 160358924 |
| NCBI Gene ID: | 9781 |
| NCBI Accession: | P50876.2 |
| UniProt Secondary Accession: | P50876,Q585H5, D6W4Y6, |
| UniProt Related Accession: | P50876 |
| Molecular Weight: | 32,890 Da |
| NCBI Full Name: | E3 ubiquitin-protein ligase RNF144A |
| NCBI Synonym Full Names: | ring finger protein 144A |
| NCBI Official Symbol: | RNF144A |
| NCBI Official Synonym Symbols: | RNF144; UBCE7IP4 |
| NCBI Protein Information: | E3 ubiquitin-protein ligase RNF144A |
| UniProt Protein Name: | E3 ubiquitin-protein ligase RNF144A |
| UniProt Synonym Protein Names: | RING finger protein 144A; UbcM4-interacting protein 4; Ubiquitin-conjugating enzyme 7-interacting protein 4 |
| Protein Family: | E3 ubiquitin-protein ligase |
| UniProt Gene Name: | RNF144A |
| UniProt Entry Name: | R144A_HUMAN |