Anti-RND3 Antibody (CAB11637)
- SKU:
- CAB11637
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RND3 Antibody |
| 抗体コード: | CAB11637 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 145-244 of human RND3 (NP_005159.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | 293T |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 145-244 of human RND3 (NP_005159.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | TLVE LSNH RQTP VSYD QGAN MAKQ IGAA TYIE CSAL QSEN SVRD IFHV ATLA CVNK TNKN VKRN KSQR ATKR ISHM PSRP ELSA VATD LRKD KAKS CTVM |
| 遺伝子ID: | 390 |
| Uniprot: | P61587 |
| セルラーロケーション: | Golgi apparatus membrane, Peripheral membrane protein |
| 計算された分子量: | 27kDa |
| 観察された分子量: | 27kDa |
| 同義語: | RND3, ARHE, Rho8, RhoE, memB |
| バックグラウンド: | This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| UniProt Protein Function: | RhoE: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. Binds ROCK1. Interacts with UBXD5. Ubiquitous. Belongs to the small GTPase superfamily. Rho family. |
| UniProt Protein Details: | Protein type:G protein, monomeric; G protein, monomeric, Rho; G protein; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2q23.3 Cellular Component: Golgi membrane; focal adhesion Molecular Function:GTPase activity; protein binding; GTP binding Biological Process: metabolic process; small GTPase mediated signal transduction; cell adhesion; actin cytoskeleton organization and biogenesis |
| NCBI Summary: | This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011] |
| UniProt Code: | P61587 |
| NCBI GenInfo Identifier: | 47606459 |
| NCBI Gene ID: | 390 |
| NCBI Accession: | P61587.1 |
| UniProt Secondary Accession: | P61587,P52199, D3DP95, |
| UniProt Related Accession: | P61587 |
| Molecular Weight: | 244 |
| NCBI Full Name: | Rho-related GTP-binding protein RhoE |
| NCBI Synonym Full Names: | Rho family GTPase 3 |
| NCBI Official Symbol: | RND3 |
| NCBI Official Synonym Symbols: | ARHE; Rho8; RhoE; memB |
| NCBI Protein Information: | rho-related GTP-binding protein RhoE; protein MemB; small GTP binding protein Rho8; ras homolog gene family, member E; rho-related GTP-binding protein Rho8 |
| UniProt Protein Name: | Rho-related GTP-binding protein RhoE |
| UniProt Synonym Protein Names: | Protein MemB; Rho family GTPase 3; Rho-related GTP-binding protein Rho8; Rnd3 |
| Protein Family: | Rho-related GTP-binding protein |
| UniProt Gene Name: | RND3 |
| UniProt Entry Name: | RND3_HUMAN |
 | Western blot analysis of extracts of 293T cells, using RND3 antibody (CAB11637) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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