Anti-RLN1 Antibody (CAB15714)
- SKU:
- CAB15714
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-RLN1 Antibody |
抗体コード: | CAB15714 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RLN1 (NP_008842.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | 22Rv1 |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RLN1 (NP_008842.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MPRL FLFH LLEF CLLL NQFS RAVA AKWK DDVI KLCG RELV RAQI AICG MSTW SKRS LSQE DAPQ TPRP VAEI VPSF INKD TETI IIML EFIA NLPP ELKA |
遺伝子ID: | 6013 |
Uniprot: | P04808 |
セルラーロケーション: | Secreted |
計算された分子量: | 13kDa/21kDa |
観察された分子量: | 20kDa |
同義語: | RLN1, H1, H1RLX, RLXH1, bA12D24.3.1, bA12D24.3.2, relaxin 1 |
バックグラウンド: | Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. |
UniProt Protein Function: | RLN1: Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix. Belongs to the insulin family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 9p24.1 |
NCBI Summary: | Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013] |
UniProt Code: | P04808 |
NCBI GenInfo Identifier: | 132280 |
NCBI Gene ID: | 6013 |
NCBI Accession: | P04808.1 |
UniProt Secondary Accession: | P04808,Q99936, Q9UQJ1, |
UniProt Related Accession: | P04808 |
Molecular Weight: | 13,011 Da |
NCBI Full Name: | Prorelaxin H1 |
NCBI Synonym Full Names: | relaxin 1 |
NCBI Official Symbol: | RLN1 |
NCBI Official Synonym Symbols: | H1; H1RLX; RLXH1; bA12D24.3.1; bA12D24.3.2 |
NCBI Protein Information: | prorelaxin H1 |
UniProt Protein Name: | Prorelaxin H1 |
Protein Family: | Prorelaxin |
UniProt Gene Name: | RLN1 |
UniProt Entry Name: | REL1_HUMAN |
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