Anti-RHBDL2 Antibody (CAB14407)
- SKU:
- CAB14407
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RHBDL2 Antibody |
| 抗体コード: | CAB14407 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 12-130 of human RHBDL2 (NP_060291.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse stomach, Rat uterus |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 12-130 of human RHBDL2 (NP_060291.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MNLN MGRE MKEE LEEE EKMR EDGG GKDR AKSK KVHR IVSK WMLP EKSR GTYL ERAN CFPP PVFI ISIS LAEL AVFI YYAV WKPQ KQWI TLDT GILE SPFI YSPE KREE AWRF ISYM LVH |
| 遺伝子ID: | 54933 |
| Uniprot: | Q9NX52 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 15kDa/34kDa |
| 観察された分子量: | 34kDa |
| 同義語: | RHBDL2, RRP2 |
| バックグラウンド: | The protein encoded by this gene is a member of the rhomboid family of integral membrane proteins. This family contains proteins that are related to Drosophila rhomboid protein. Members of this family are found in both prokaryotes and eukaryotes and are thought to function as intramembrane serine proteases. The encoded protein is thought to release soluble growth factors by proteolytic cleavage of certain membrane-bound substrates, including ephrin B2 and ephrin B3. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | RHBDL2: Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Known substrate: EFNB3. Belongs to the peptidase S54 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.4.21.105; Membrane protein, integral; Membrane protein, multi-pass; Protease Chromosomal Location of Human Ortholog: 1p34.3 Cellular Component: integral to membrane; plasma membrane Molecular Function:serine-type endopeptidase activity Biological Process: protein processing |
| NCBI Summary: | The protein encoded by this gene is a member of the rhomboid family of integral membrane proteins. This family contains proteins that are related to Drosophila rhomboid protein. Members of this family are found in both prokaryotes and eukaryotes and are thought to function as intramembrane serine proteases. The encoded protein is thought to release soluble growth factors by proteolytic cleavage of certain membrane-bound substrates, including ephrin B2 and ephrin B3. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015] |
| UniProt Code: | Q9NX52 |
| NCBI GenInfo Identifier: | 54144654 |
| NCBI Gene ID: | 54933 |
| NCBI Accession: | NP_060291.2 |
| UniProt Secondary Accession: | Q9NX52,Q6P175, Q8NER8, Q96E02, B2RNT3, B9EH75, |
| UniProt Related Accession: | Q9NX52 |
| Molecular Weight: | 18.3kD |
| NCBI Full Name: | rhomboid-related protein 2 isoform 2 |
| NCBI Synonym Full Names: | rhomboid like 2 |
| NCBI Official Symbol: | RHBDL2 |
| NCBI Official Synonym Symbols: | RRP2 |
| NCBI Protein Information: | rhomboid-related protein 2 |
| UniProt Protein Name: | Rhomboid-related protein 2 |
| UniProt Synonym Protein Names: | Rhomboid-like protein 2 |
| Protein Family: | Rhomboid-related protein |
| UniProt Gene Name: | RHBDL2 |
 | Western blot analysis of extracts of various cell lines, using RHBDL2 antibody (CAB14407) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 40s. |
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