Anti-RHBDL1 Antibody (CAB16084)
- SKU:
- CAB16084
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RHBDL1 Antibody |
| 抗体コード: | CAB16084 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human RHBDL1 |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Mouse kidney, Mouse testis, Rat brain, Rat kidney |
| 免疫原: | Recombinant protein of human RHBDL1 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 9028 |
| Uniprot: | O75783 |
| セルラーロケーション: | Membrane, Multi-pass membrane protein |
| 計算された分子量: | 41kDa/48kDa |
| 観察された分子量: | 48kDa |
| 同義語: | RHBDL1, RHBDL, RRP |
| バックグラウンド: | This gene encodes a protein similar to Rhomboid in Drosophila which is involved in signalling in the Spitz/epidermal growth factor receptor/mitogen-activated protein kinase pathway. The Rhomboid family of proteins consists of intramembrane serine proteases containing several transmembrane domains. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | RHBDL1: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Belongs to the peptidase S54 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; EC 3.4.21.105; Protease; Membrane protein, integral Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: integral to plasma membrane; membrane; mitochondrial inner membrane Molecular Function:serine-type endopeptidase activity Biological Process: protein processing; signal transduction |
| NCBI Summary: | This gene encodes a protein similar to Rhomboid in Drosophila which is involved in signalling in the Spitz/epidermal growth factor receptor/mitogen-activated protein kinase pathway. The Rhomboid family of proteins consists of intramembrane serine proteases containing several transmembrane domains. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] |
| UniProt Code: | O75783 |
| NCBI GenInfo Identifier: | 20139374 |
| NCBI Gene ID: | 9028 |
| NCBI Accession: | O75783.1 |
| UniProt Secondary Accession: | O75783,Q0VAX4, Q9NQ85, A2IDC0, A2IDC1, |
| UniProt Related Accession: | O75783 |
| Molecular Weight: | 41,720 Da |
| NCBI Full Name: | Rhomboid-related protein 1 |
| NCBI Synonym Full Names: | rhomboid like 1 |
| NCBI Official Symbol: | RHBDL1 |
| NCBI Official Synonym Symbols: | RRP; RHBDL |
| NCBI Protein Information: | rhomboid-related protein 1 |
| UniProt Protein Name: | Rhomboid-related protein 1 |
| UniProt Synonym Protein Names: | Rhomboid-like protein 1 |
| UniProt Gene Name: | RHBDL1 |
| UniProt Entry Name: | RHBL1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RHBDL1 antibody (CAB16084) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
View AllClose