Anti-RGMB Antibody (CAB12859)
- SKU:
- CAB12859
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RGMB Antibody |
| 抗体コード: | CAB12859 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-453 of human RGMB (NP_001012779.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-453 of human RGMB (NP_001012779.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PHLR TFKD NFQT CKVE GAWP LIDN NYLS VQVT NVPV VPGS SATA TNKI TIIF KAHH ECTD QKVY QAVT DDLP AAFV DGTT SGGD SDAK SLRI VERE SGHY VEMH ARYI GTTV FVRQ VGRY LTLA IRMP EDLA MSYE ESQD LQLC VNGC PLSE RIDD GQGQ VSAI LGHS LPRT SLVQ AWPG YTLE TANT QCHE KMPV KDIY FQSC VFDL LTTG DANF TAAA HSAL EDVE ALHP RKER WHIF PSSG |
| 遺伝子ID: | 285704 |
| Uniprot: | Q6NW40 |
| セルラーロケーション: | Cell membrane, GPI-anchor, Lipid-anchor, Membrane raft |
| 計算された分子量: | 47kDa |
| 観察された分子量: | 47kDa |
| 同義語: | RGMB, DRAGON |
| バックグラウンド: |
| UniProt Protein Function: | RGMB: Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system. Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling. Promotes neuronal adhesion. May inhibit neurite outgrowth. Belongs to the repulsive guidance molecule (RGM) family. |
| UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, GPI anchor; Transcription regulation Chromosomal Location of Human Ortholog: 5q15 Cellular Component: anchored to plasma membrane; ER-Golgi intermediate compartment; plasma membrane Molecular Function:coreceptor activity; identical protein binding Biological Process: BMP signaling pathway; cell adhesion; positive regulation of transcription, DNA-dependent; signal transduction |
| NCBI Summary: | RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 [PubMed 15671031]).[supplied by OMIM, Apr 2009] |
| UniProt Code: | Q6NW40 |
| NCBI GenInfo Identifier: | 327478562 |
| NCBI Gene ID: | 285704 |
| NCBI Accession: | Q6NW40.3 |
| UniProt Secondary Accession: | Q6NW40,Q8NC92, D6R9A0, |
| UniProt Related Accession: | Q6NW40 |
| Molecular Weight: | 48kDa |
| NCBI Full Name: | RGM domain family member B |
| NCBI Synonym Full Names: | repulsive guidance molecule family member b |
| NCBI Official Symbol: | RGMB |
| NCBI Official Synonym Symbols: | DRAGON |
| NCBI Protein Information: | RGM domain family member B |
| UniProt Protein Name: | RGM domain family member B |
| UniProt Synonym Protein Names: | DRG11-responsive axonal guidance and outgrowth of neurite; DRAGON |
| Protein Family: | RGM domain family |
| UniProt Gene Name: | RGMB |
 | Western blot analysis of extracts of various cell lines, using RGMB antibody (CAB12859) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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