Anti-RFC3 Antibody (CAB4075)
- SKU:
- CAB4075
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-RFC3 Antibody |
| 抗体コード: | CAB4075 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human RFC3 (NP_002906.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | MCF-7, SW480, HL-60, NIH/3T3, 293T, Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human RFC3 (NP_002906.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSLW VDKY RPCS LGRL DYHK EQAA QLRN LVQC GDFP HLLV YGPS GAGK KTRI MCIL RELY GVGV EKLR IEHQ TITT PSKK KIEI STIA SNYH LEVN PSDA GNSD RVVI QEML KTVA QSQQ LETN SQRD FKVV LLTE VDKL TKDA QHAL RRTM EKYM STCR LILC CNST SKVI PPIR SRCL AVRV PAPS IEDI CHVL STVC KKEG LNLP SQLA HRLA EKSC RNLR KALL MCEA CRVQ QYPF TADQ EIPE TDWE VYLR ETAN AIVS QQTP QRLL EVRG RLYE |
| 遺伝子ID: | 5983 |
| Uniprot: | P40938 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 34kDa/40kDa |
| 観察された分子量: | 41kDa |
| 同義語: | RFC3, RFC38 |
| バックグラウンド: | The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
| UniProt Protein Function: | RFC3: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. Belongs to the activator 1 small subunits family. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 13q13.2 Cellular Component: nucleoplasm; DNA replication factor C complex; nucleus Molecular Function:protein binding; DNA binding; ATPase activity; DNA clamp loader activity Biological Process: telomere maintenance via semi-conservative replication; DNA synthesis during DNA repair; response to organophosphorus; nucleotide-excision repair; transcription-coupled nucleotide-excision repair; telomere maintenance via recombination; mitotic cell cycle; nucleotide-excision repair, DNA gap filling; DNA strand elongation during DNA replication; DNA repair; DNA replication; telomere maintenance |
| NCBI Summary: | The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P40938 |
| NCBI GenInfo Identifier: | 3915601 |
| NCBI Gene ID: | 5983 |
| NCBI Accession: | P40938.2 |
| UniProt Secondary Accession: | P40938,O15252, Q5W0E8, C9JU95, |
| UniProt Related Accession: | P40938 |
| Molecular Weight: | 356 |
| NCBI Full Name: | Replication factor C subunit 3 |
| NCBI Synonym Full Names: | replication factor C (activator 1) 3, 38kDa |
| NCBI Official Symbol: | RFC3 |
| NCBI Official Synonym Symbols: | RFC38 |
| NCBI Protein Information: | replication factor C subunit 3; A1 38 kDa subunit; RFC, 38 kD subunit; RF-C 38 kDa subunit; activator 1 subunit 3; activator 1 38 kDa subunit; replication factor C 38 kDa subunit |
| UniProt Protein Name: | Replication factor C subunit 3 |
| UniProt Synonym Protein Names: | Activator 1 38 kDa subunit; A1 38 kDa subunit; Activator 1 subunit 3; Replication factor C 38 kDa subunit; RF-C 38 kDa subunit; RFC38 |
| Protein Family: | Replication factor |
| UniProt Gene Name: | RFC3 |
| UniProt Entry Name: | RFC3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RFC3 antibody (CAB4075) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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