Anti-REXO2 Antibody (CAB15808)
- SKU:
- CAB15808
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-REXO2 Antibody |
抗体コード: | CAB15808 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-237 of human REXO2 (NP_056338.2). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | 293T, U-87MG, LO2, HT-29 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-237 of human REXO2 (NP_056338.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | VREG GAAM AAGE SMAQ RMVW VDLE MTGL DIEK DQII EMAC LITD SDLN ILAE GPNL IIKQ PDEL LDSM SDWC KEHH GKSG LTKA VKES TITL QQAE YEFL SFVR QQTP PGLC PLAG NSVH EDKK FLDK YMPQ FMKH LHYR IIDV STVK ELCR RWYP EEYE FAPK KAAS HRAL DDIS ESIK ELQF YRNN IFKK KIDE KKRK IIEN GENE KTVS |
遺伝子ID: | 25996 |
Uniprot: | Q9Y3B8 |
セルラーロケーション: | Cytoplasm, Mitochondrion intermembrane space, Mitochondrion matrix, Nucleus |
計算された分子量: | 23kDa/26kDa |
観察された分子量: | 27kDa |
同義語: | REXO2, CGI-114, REX2, RFN, SFN |
バックグラウンド: | This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. |
UniProt Protein Function: | REXO2: a 3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily=5 nucleotides in length) single-stranded RNA and DNA oligomers. May have a role for cellular nucleotide recycling. Two splice variant isoforms have been described: mitochondrial (isoform 1) and nuclear (isoform 2). |
UniProt Protein Details: | Protein type:EC 3.1.-.-; Hydrolase Chromosomal Location of Human Ortholog: 11q23.2 Cellular Component: focal adhesion; mitochondrion; nucleolus; nucleus Molecular Function:3'-5' exonuclease activity; 3'-5'-exoribonuclease activity Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; nucleotide metabolic process |
NCBI Summary: | This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. [provided by RefSeq, Nov 2011] |
UniProt Code: | Q9Y3B8 |
NCBI GenInfo Identifier: | 116242694 |
NCBI Gene ID: | 25996 |
NCBI Accession: | Q9Y3B8.3 |
UniProt Secondary Accession: | Q9Y3B8,Q32Q18, Q53FT1, Q6FIC6, Q9UFY7, B2R532, |
UniProt Related Accession: | Q9Y3B8 |
Molecular Weight: | 23,754 Da |
NCBI Full Name: | Oligoribonuclease, mitochondrial |
NCBI Synonym Full Names: | RNA exonuclease 2 |
NCBI Official Symbol: | REXO2 |
NCBI Official Synonym Symbols: | RFN; SFN; REX2; CGI-114 |
NCBI Protein Information: | oligoribonuclease, mitochondrial |
UniProt Protein Name: | Oligoribonuclease, mitochondrial |
UniProt Synonym Protein Names: | RNA exonuclease 2 homolog; Small fragment nuclease |
UniProt Gene Name: | REXO2 |
UniProt Entry Name: | ORN_HUMAN |
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