Anti-RETN Antibody (CAB2551)
- SKU:
- CAB2551
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RETN Antibody |
| 抗体コード: | CAB2551 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human RETN (NP_001180303.1). |
| 申し込み: | IHC |
| 推奨希釈: | IHC 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human RETN (NP_001180303.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MKAL CLLL LPVL GLLV SSKT LCSM EEAI NERI QEVA GSLI FRAI SSIG LECQ SVTS RGDL ATCP RGFA VTGC TCGS ACGS WDVR AETT CHCQ CAGM DWTG ARCC RVQP |
| 遺伝子ID: | 56729 |
| Uniprot: | Q9HD89 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 8kDa/11kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | RETN, ADSF, FIZZ3, RETN1, RSTN, XCP1, resistin |
| バックグラウンド: | This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| UniProt Protein Function: | resistin: Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes. Belongs to the resistin/FIZZ family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: extracellular space; nucleus Molecular Function:hormone activity Biological Process: fat cell differentiation; response to mechanical stimulus; positive regulation of smooth muscle cell proliferation; positive regulation of smooth muscle cell migration; positive regulation of synaptic transmission; aging; response to insulin stimulus Disease: Diabetes Mellitus, Noninsulin-dependent |
| NCBI Summary: | This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010] |
| UniProt Code: | Q9HD89 |
| NCBI GenInfo Identifier: | 18202962 |
| NCBI Gene ID: | 56729 |
| NCBI Accession: | Q9HD89.1 |
| UniProt Secondary Accession: | Q9HD89,Q540D9, Q76B53, D6W649, |
| UniProt Related Accession: | Q9HD89 |
| Molecular Weight: | 8,686 Da |
| NCBI Full Name: | Resistin |
| NCBI Synonym Full Names: | resistin |
| NCBI Official Symbol: | RETN |
| NCBI Official Synonym Symbols: | ADSF; RSTN; XCP1; FIZZ3; RETN1 |
| NCBI Protein Information: | resistin; resistin delta2; found in inflammatory zone 3; cysteine-rich secreted protein FIZZ3; adipose tissue-specific secretory factor; cysteine-rich secreted protein A12-alpha-like 2; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1 |
| UniProt Protein Name: | Resistin |
| UniProt Synonym Protein Names: | Adipose tissue-specific secretory factor; ADSF; C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like 2; Cysteine-rich secreted protein FIZZ3 |
| Protein Family: | Resistin |
| UniProt Gene Name: | RETN |
| UniProt Entry Name: | RETN_HUMAN |
 | Immunohistochemistry of paraffin-embedded human stomach using RETN antibody (CAB2551) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse lung using RETN antibody (CAB2551) at dilution of 1:100 (40x lens). |
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