Anti-RECQL4 Antibody (CAB14823)
- SKU:
- CAB14823
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RECQL4 Antibody |
| 抗体コード: | CAB14823 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 231-330 of human RECQL4 (NP_004251.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 231-330 of human RECQL4 (NP_004251.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | GAGS QGPE ASAF QEVS IRVG SPQP SSSG GEKR RWNE EPWE SPAQ VQQE SSQA GPPS EGAG AVAV EEDP PGEP VQAQ PPQP CSSP SNPR YHGL SPSS QARA |
| 遺伝子ID: | 9401 |
| Uniprot: | O94761 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 133kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | RECQL4, RECQ4 |
| バックグラウンド: | The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is predominantly expressed in thymus and testis. Mutations in this gene are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes. |
| UniProt Protein Function: | RECQL4: DNA-dependent ATPase. May modulate chromosome segregation. Interacts with UBR1 and UBR2. Interacts with MCM10; this interaction regulates RECQL4 unwinding activity. Up-regulated in actively dividing cells. Ubiquitously expressed, with highest levels in thymus and testis. Belongs to the helicase family. RecQ subfamily. |
| UniProt Protein Details: | Protein type:Helicase; EC 3.6.4.12 Chromosomal Location of Human Ortholog: 8q24.3 Cellular Component: membrane; cytoplasm; nucleus Molecular Function:ATP-dependent 3'-5' DNA helicase activity; zinc ion binding; bubble DNA binding; ATP binding Biological Process: multicellular organismal development; DNA strand renaturation; DNA replication; DNA repair; DNA duplex unwinding; DNA recombination Disease: Rapadilino Syndrome; Rothmund-thomson Syndrome; Baller-gerold Syndrome |
| NCBI Summary: | The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is predominantly expressed in thymus and testis. Mutations in this gene are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes. [provided by RefSeq, Jan 2010] |
| UniProt Code: | O94761 |
| NCBI GenInfo Identifier: | 18206225 |
| NCBI Gene ID: | 9401 |
| NCBI Accession: | O94761.1 |
| UniProt Secondary Accession: | O94761,Q3Y424, Q96DW2, Q96F55, |
| UniProt Related Accession: | O94761 |
| Molecular Weight: | 1208 |
| NCBI Full Name: | ATP-dependent DNA helicase Q4 |
| NCBI Synonym Full Names: | RecQ protein-like 4 |
| NCBI Official Symbol: | RECQL4 |
| NCBI Official Synonym Symbols: | RECQ4 |
| NCBI Protein Information: | ATP-dependent DNA helicase Q4; DNA helicase, RecQ-like type 4; DNA helicase, RecQ-like, type 4 |
| UniProt Protein Name: | ATP-dependent DNA helicase Q4 |
| UniProt Synonym Protein Names: | DNA helicase, RecQ-like type 4; RecQ4; RTS; RecQ protein-like 4 |
| Protein Family: | ATP-dependent DNA helicase |
| UniProt Gene Name: | RECQL4 |
| UniProt Entry Name: | RECQ4_HUMAN |
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