Anti-RDH10 Antibody (CAB12136)
- SKU:
- CAB12136
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RDH10 Antibody |
| 抗体コード: | CAB12136 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-293 of human RDH10 (NP_742034.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, 293T, HT-29, HepG2, Mouse spleen |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-293 of human RDH10 (NP_742034.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VRPK EKSV AGQV CLIT GAGS GLGR LFAL EFAR RRAL LVLW DINT QSNE ETAG MVRH IYRD LEAA DAAA LQAG NGEE EILP HCNL QVFT YTCD VGKR ENVY LTAE RVRK EVGE VSVL VNNA GVVS GHHL LECP DELI ERTM MVNC HAHF WTTK AFLP TMLE INHG HIVT VASS LGLF STAG VEDY CASK FGVV GFHE SLSH ELKA AEKD GIKT TLVC PYLV DTGM FRGC RIRK EIEP FLPP LKPD YCVK QAMK AILT DQPM ICTP RLM |
| 遺伝子ID: | 157506 |
| Uniprot: | Q8IZV5 |
| セルラーロケーション: | Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein |
| 計算された分子量: | 38kDa |
| 観察された分子量: | 38kDa |
| 同義語: | RDH10, SDR16C4 |
| バックグラウンド: | This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. |
| UniProt Protein Function: | RDH10: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol. Belongs to the short-chain dehydrogenases/reductases (SDR) family. |
| UniProt Protein Details: | Protein type:Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.300; Membrane protein, integral; Oxidoreductase Chromosomal Location of Human Ortholog: 8q21.11 Cellular Component: cytoplasm; endoplasmic reticulum membrane; integral to membrane; nucleus Molecular Function:retinol dehydrogenase activity Biological Process: retinal metabolic process; retinoid metabolic process; retinol metabolic process; visual perception |
| NCBI Summary: | This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. [provided by RefSeq, Dec 2011] |
| UniProt Code: | Q8IZV5 |
| NCBI GenInfo Identifier: | 74750799 |
| NCBI Gene ID: | 157506 |
| NCBI Accession: | Q8IZV5.1 |
| UniProt Related Accession: | Q8IZV5 |
| Molecular Weight: | 38kDa |
| NCBI Full Name: | Retinol dehydrogenase 10 |
| NCBI Synonym Full Names: | retinol dehydrogenase 10 |
| NCBI Official Symbol: | RDH10 |
| NCBI Official Synonym Symbols: | SDR16C4 |
| NCBI Protein Information: | retinol dehydrogenase 10 |
| UniProt Protein Name: | Retinol dehydrogenase 10 |
| UniProt Synonym Protein Names: | Short chain dehydrogenase/reductase family 16C member 4 |
| Protein Family: | Retinol dehydrogenase |
| UniProt Gene Name: | RDH10 |
 | Western blot analysis of extracts of various cell lines, using RDH10 antibody (CAB12136) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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