Anti-RBMS3 Antibody (CAB17142)
- SKU:
- CAB17142
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RBMS3 Antibody |
| 抗体コード: | CAB17142 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 334-433 of human RBMS3 (NP_001171183.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 334-433 of human RBMS3 (NP_001171183.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MDHP MSMQ PANM MGPL TQQM NHLS LGTT GTYM TAAA PMQG TYIP QYTP VPPT AVSI EGVV ADTS PQTV APSS QDTS GQQQ QIAV DTSN EHAP AYSY QQSK |
| 遺伝子ID: | 27303 |
| Uniprot: | Q6XE24 |
| セルラーロケーション: | |
| 計算された分子量: | 45kDa/47kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | RBMS3 |
| バックグラウンド: | This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | RBMS3: Binds poly(A) and poly(U) oligoribonucleotides. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3p24-p23 Cellular Component: cytoplasm Molecular Function:mRNA 3'-UTR binding; nucleotide binding Biological Process: positive regulation of translation |
| NCBI Summary: | This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010] |
| UniProt Code: | Q6XE24 |
| NCBI GenInfo Identifier: | 74762382 |
| NCBI Gene ID: | 27303 |
| NCBI Accession: | Q6XE24.1 |
| UniProt Related Accession: | Q6XE24 |
| Molecular Weight: | 45kDa; 47kDa |
| NCBI Full Name: | RNA-binding motif, single-stranded-interacting protein 3 |
| NCBI Synonym Full Names: | RNA binding motif single stranded interacting protein 3 |
| NCBI Official Symbol: | RBMS3 |
| NCBI Protein Information: | RNA-binding motif, single-stranded-interacting protein 3 |
| UniProt Protein Name: | RNA-binding motif, single-stranded-interacting protein 3 |
| Protein Family: | RNA-binding motif, single-stranded-interacting protein |
| UniProt Gene Name: | RBMS3 |
| UniProt Entry Name: | RBMS3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RBMS3 antibody (CAB17142) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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