Anti-RBM17 Antibody (CAB3240)
- SKU:
- CAB3240
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-RBM17 Antibody |
抗体コード: | CAB3240 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human RBM17 (NP_116294.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | LO2, A-549, HeLa, DU145, Rat thymus |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human RBM17 (NP_116294.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MSLY DDLG VETS DSKT EGWS KNFK LLQS QLQV KKAA LTQA KSQR TKQS TVLA PVID LKRG GSSD DRQI VDTP PHVA AGLK DPVP SGFS AGEV LIPL ADEY DPMF PNDY EKVV KRQR EERQ RQRE LERQ KEIE EREK RRKD RHEA SGFA RRPD PDSD EDED YERE RRKR SMGG AAIA PPTS LVEK DKEL PRDF PYEE DSRP RSQS SKAA IPPP VYEE QDRP RSPT GPSN SFLA NMGG TVAH |
遺伝子ID: | 84991 |
Uniprot: | Q96I25 |
セルラーロケーション: | Nucleus |
計算された分子量: | 44kDa |
観察された分子量: | 50kDa |
同義語: | RBM17, SPF45 |
バックグラウンド: | This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. |
UniProt Protein Function: | RBM17: Splice factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia. |
UniProt Protein Details: | Protein type:RNA splicing; RNA-binding; Spliceosome Chromosomal Location of Human Ortholog: 10p15.1 Cellular Component: nucleoplasm; spliceosome Molecular Function:protein binding; RNA binding; nucleotide binding Biological Process: alternative nuclear mRNA splicing, via spliceosome |
NCBI Summary: | This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009] |
UniProt Code: | Q96I25 |
NCBI GenInfo Identifier: | 34925383 |
NCBI Gene ID: | 84991 |
NCBI Accession: | Q96I25.1 |
UniProt Secondary Accession: | Q96I25,Q96GY6, |
UniProt Related Accession: | Q96I25 |
Molecular Weight: | 401 |
NCBI Full Name: | Splicing factor 45 |
NCBI Synonym Full Names: | RNA binding motif protein 17 |
NCBI Official Symbol: | RBM17 |
NCBI Official Synonym Symbols: | SPF45 |
NCBI Protein Information: | splicing factor 45; splicing factor 45kDa; 45 kDa-splicing factor; RNA-binding motif protein 17 |
UniProt Protein Name: | Splicing factor 45 |
UniProt Synonym Protein Names: | 45 kDa-splicing factor; RNA-binding motif protein 17 |
Protein Family: | Splicing factor |
UniProt Gene Name: | RBM17 |
UniProt Entry Name: | SPF45_HUMAN |
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