Anti-RBM15B Antibody (CAB9873)
- SKU:
- CAB9873
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-RBM15B Antibody |
| 抗体コード: | CAB9873 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 540-720 of human RBM15B (NP_037418.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HT-29, SH-SY5Y, HepG2, BT-474, Mouse pancreas, Mouse lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 540-720 of human RBM15B (NP_037418.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | DRDR TFLE GDWT SPSK SSDR RNSL EGYS RSVR SRSG ERWG ADGD RGLP KPWE ERRK RRSL SSDR GRTT HSPY EERS RTKG SGQQ SERG SDRT PERS RKEN HSSE GTKE SSSN SLSN SRHG AEER GHHH HHHE AADS SHGK KARD SERN HRTT EAEP KPLE EPKH ETKK LKNL SEYA QTLQ L |
| 遺伝子ID: | 29890 |
| Uniprot: | Q8NDT2 |
| セルラーロケーション: | Nucleus, nucleoplasm |
| 計算された分子量: | 63kDa/97kDa |
| 観察された分子量: | 97kDa/107kDa |
| 同義語: | RBM15B, HUMAGCGB, OTT3 |
| バックグラウンド: |
| UniProt Protein Function: | RBM15B: May function in the regulation of alternative or illicit splicing. Belongs to the RRM Spen family. |
| UniProt Protein Details: | Protein type:RNA splicing; RNA-binding Chromosomal Location of Human Ortholog: 3p21.2 Cellular Component: nucleolus; nucleoplasm Molecular Function:nucleic acid binding; protein binding; RNA binding Biological Process: negative regulation of transcription, DNA-dependent; nucleocytoplasmic transport; regulation of alternative nuclear mRNA splicing, via spliceosome |
| NCBI Summary: | Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009] |
| UniProt Code: | Q8NDT2 |
| NCBI GenInfo Identifier: | 229463030 |
| NCBI Gene ID: | 29890 |
| NCBI Accession: | Q8NDT2.3 |
| UniProt Secondary Accession: | Q8NDT2,Q6QE19, Q9BV96, A4QPG7, |
| UniProt Related Accession: | Q8NDT2 |
| Molecular Weight: | 97kDa |
| NCBI Full Name: | Putative RNA-binding protein 15B |
| NCBI Synonym Full Names: | RNA binding motif protein 15B |
| NCBI Official Symbol: | RBM15B |
| NCBI Official Synonym Symbols: | OTT3; HUMAGCGB |
| NCBI Protein Information: | putative RNA-binding protein 15B |
| UniProt Protein Name: | Putative RNA-binding protein 15B |
| UniProt Synonym Protein Names: | One-twenty two protein 3; HuOTT3; RNA-binding motif protein 15B |
| Protein Family: | Putative RNA-binding protein |
| UniProt Gene Name: | RBM15B |
 | Western blot analysis of extracts of various cell lines, using RBM15B Antibody (CAB9873) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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