Anti-RASAL2 Antibody (CAB15120)
- SKU:
- CAB15120
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RASAL2 Antibody |
| 抗体コード: | CAB15120 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 750-1040 of human RASAL2 (NP_733793.2). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human, Rat |
| ポジティブサンプル: | HeLa |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 750-1040 of human RASAL2 (NP_733793.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LADI TKSL TNPT PIQQ QLRR FTEH NSSP NVSG SLSS GLQK IFED PTDS DLHK LKSP SQDN TDSY FRGK TLLL VQQA SSQS MTYS EKDE RESS LPNG RSVS LMDL QDTH AAQV EHAS VMLD VPIR LTGS QLSI TQVA SIKQ LRET QSTP QSAP QVRR PLHP ALNQ PGGL QPLS FQNP VYHL NNPI PAMP KASI DSSL ENLS TASS RSQS NSED FKLS GPSN SSME DFTK RSTQ SEDF SRRH TVPD RHIP LALP RQNS TGQA QIRK VDQG GLGA RAKA PPSL PHSA SLRS TGS |
| 遺伝子ID: | 9462 |
| Uniprot: | Q9UJF2 |
| セルラーロケーション: | |
| 計算された分子量: | 128kDa/143kDa |
| 観察された分子量: | 160kDa |
| 同義語: | RASAL2, NGAP |
| バックグラウンド: | This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| UniProt Protein Function: | RASAL2: Inhibitory regulator of the Ras-cyclic AMP pathway. |
| UniProt Protein Details: | Protein type:GAPs, Ras; GAPs Chromosomal Location of Human Ortholog: 1q24 Cellular Component: cytoplasm; cytosol Molecular Function:protein binding Biological Process: MAPKKK cascade; negative regulation of Ras protein signal transduction; signal transduction |
| NCBI Summary: | This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UJF2 |
| NCBI GenInfo Identifier: | 13959419 |
| NCBI Gene ID: | 9462 |
| NCBI Accession: | Q9UJF2.2 |
| UniProt Secondary Accession: | Q9UJF2,O95174, Q2TB22, Q5TFU9, F8W755, |
| UniProt Related Accession: | Q9UJF2 |
| Molecular Weight: | 143,899 Da |
| NCBI Full Name: | Ras GTPase-activating protein nGAP |
| NCBI Synonym Full Names: | RAS protein activator like 2 |
| NCBI Official Symbol: | RASAL2 |
| NCBI Official Synonym Symbols: | NGAP |
| NCBI Protein Information: | ras GTPase-activating protein nGAP |
| UniProt Protein Name: | Ras GTPase-activating protein nGAP |
| UniProt Synonym Protein Names: | RAS protein activator-like 2 |
| Protein Family: | Ras GTPase-activating protein |
| UniProt Gene Name: | RASAL2 |
| UniProt Entry Name: | NGAP_HUMAN |
 | Western blot analysis of extracts of HeLa cells, using RASAL2 antibody (CAB15120) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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