Anti-RALGDS Antibody (CAB17963)
- SKU:
- CAB17963
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
抗体名: | Anti-RALGDS Antibody |
抗体コード: | CAB17963 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant protein of human RALGDS. |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-87MG, Mouse ovary, Mouse lung |
免疫原: | Recombinant protein of human RALGDS. |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 5900 |
Uniprot: | Q12967 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | 110kDa |
同義語: | RGDS, RGF, RalGEF, RALGDS |
バックグラウンド: | Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.[supplied by OMIM, Nov 2010] |
UniProt Protein Function: | RALGDS: Stimulates the dissociation of GDP from the Ras-related RalA and RalB GTPases which allows GTP binding and activation of the GTPases. Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:GEFs, Ras; GEFs Chromosomal Location of Human Ortholog: 9q34.3 Cellular Component: brush border; cytosol; nucleus Molecular Function:GTPase regulator activity; protein binding Biological Process: Ras protein signal transduction |
NCBI Summary: | Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.[supplied by OMIM, Nov 2010] |
UniProt Code: | Q12967 |
NCBI GenInfo Identifier: | 14549162 |
NCBI Gene ID: | 5900 |
NCBI Accession: | Q12967.2 |
UniProt Secondary Accession: | Q12967,Q5T7V4, Q6KH11, Q6PCE1, Q6ZSD5, Q9HAX7, Q9HAY1 Q9HCT1, Q9P2N8, B7Z753, E7ER93, E7ERZ0, |
UniProt Related Accession: | Q12967 |
Molecular Weight: | 99,325 Da |
NCBI Full Name: | Ral guanine nucleotide dissociation stimulator |
NCBI Synonym Full Names: | ral guanine nucleotide dissociation stimulator |
NCBI Official Symbol: | RALGDS |
NCBI Official Synonym Symbols: | RGF; RGDS; RalGEF |
NCBI Protein Information: | ral guanine nucleotide dissociation stimulator |
UniProt Protein Name: | Ral guanine nucleotide dissociation stimulator |
UniProt Synonym Protein Names: | Ral guanine nucleotide exchange factor; RalGEF |
Protein Family: | Ral guanine nucleotide dissociation stimulator |
UniProt Gene Name: | RALGDS |
UniProt Entry Name: | GNDS_HUMAN |