Anti-RAB8B Antibody (CAB3678)
- SKU:
- CAB3678
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RAB8B Antibody |
| 抗体コード: | CAB3678 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human RAB8B (NP_057614.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:1000 |
| 反応性: | Human |
| ポジティブサンプル: | U-87MG |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human RAB8B (NP_057614.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAKT YDYL FKLL LIGD SGVG KTCL LFRF SEDA FNTT FIST IGID FKIR TIEL DGKK IKLQ IWDT AGQE RFRT ITTA YYRG AMGI MLVY DITN EKSF DNIK NWIR NIEE HASS DVER MILG NKCD MNDK RQVS KERG EKLA IDYG IKFL ETSA KSSA NVEE AFFT LARD IMTK LNRK MNDS NSAG AGGP VKIT ENRS KKTS FFRC SLL |
| 遺伝子ID: | 51762 |
| Uniprot: | Q92930 |
| セルラーロケーション: | Cell membrane, Cytoplasmic side, Cytoplasmic vesicle, Lipid-anchor, phagosome, phagosome membrane |
| 計算された分子量: | 23kDa |
| 観察された分子量: | 23KDa |
| 同義語: | RAB8B |
| バックグラウンド: | RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al., 1997 [PubMed 9030196]).[supplied by OMIM, Nov 2010] |
| UniProt Protein Function: | RAB8B: May be involved in vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells. Belongs to the small GTPase superfamily. Rab family. |
| UniProt Protein Details: | Protein type:G protein, monomeric; Motility/polarity/chemotaxis; G protein, monomeric, Rab; G protein Chromosomal Location of Human Ortholog: 15q22.2 Cellular Component: peroxisomal membrane; phagocytic vesicle Molecular Function:GDP binding; protein binding; receptor binding Biological Process: antigen processing and presentation; cilium biogenesis; protein import into peroxisome membrane; protein secretion; vesicle docking during exocytosis |
| NCBI Summary: | RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al., 1997 [PubMed 9030196]).[supplied by OMIM, Nov 2010] |
| UniProt Code: | Q92930 |
| NCBI GenInfo Identifier: | 13638434 |
| NCBI Gene ID: | 51762 |
| NCBI Accession: | Q92930.2 |
| UniProt Secondary Accession: | Q92930,Q5JPC4, Q9P293, |
| UniProt Related Accession: | Q92930 |
| Molecular Weight: | 23,584 Da |
| NCBI Full Name: | Ras-related protein Rab-8B |
| NCBI Synonym Full Names: | RAB8B, member RAS oncogene family |
| NCBI Official Symbol: | RAB8B |
| NCBI Protein Information: | ras-related protein Rab-8B |
| UniProt Protein Name: | Ras-related protein Rab-8B |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB8B |
| UniProt Entry Name: | RAB8B_HUMAN |
 | Western blot analysis of extracts of U-87MG cells, using RAB8B Rabbit pAb (CAB3678) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |
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