Anti-RAB5C Antibody (CAB7342)
- SKU:
- CAB7342
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RAB5C Antibody |
| 抗体コード: | CAB7342 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human RAB5C (NP_958842.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, BT-474, HL-60, Mouse lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human RAB5C (NP_958842.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAGR GGAA RPNG PAAG NKIC QFKL VLLG ESAV GKSS LVLR FVKG QFHE YQES TIGA AFLT QTVC LDDT TVKF EIWD TAGQ ERYH SLAP MYYR GAQA AIVV YDIT NTDT FARA KNWV KELQ RQAS PNIV IALA GNKA DLAS KRAV EFQE AQAY ADDN SLLF METS AKTA MNVN EIFM AIAK KLPK NEPQ NATG APGR NRGV DLQE NNPA SRSQ CCSN |
| 遺伝子ID: | 5878 |
| Uniprot: | P51148 |
| セルラーロケーション: | Cell membrane, Cytoplasmic side, Early endosome membrane, Lipid-anchor, Melanosome |
| 計算された分子量: | 23kDa/27kDa |
| 観察された分子量: | 23kDa |
| 同義語: | RAB5C, L1880, RAB5CL, RAB5L, RABL |
| バックグラウンド: |
| UniProt Protein Function: | RAB5C: Protein transport. Probably involved in vesicular traffic. Belongs to the small GTPase superfamily. Rab family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; G protein, monomeric; G protein; G protein, monomeric, Rab Chromosomal Location of Human Ortholog: 17q21.2 Cellular Component: early endosome; endocytic vesicle; intracellular membrane-bound organelle; lipid particle; lysosomal membrane; plasma membrane Molecular Function:GDP binding; GTPase activity; protein binding Biological Process: plasma membrane to endosome transport; regulation of endocytosis |
| NCBI Summary: | Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010] |
| UniProt Code: | P51148 |
| NCBI GenInfo Identifier: | 38258923 |
| NCBI Gene ID: | 5878 |
| NCBI Accession: | P51148.2 |
| UniProt Secondary Accession: | P51148,Q6FH55, Q9P0Y5, F8W1H5, |
| UniProt Related Accession: | P51148 |
| Molecular Weight: | 27,036 Da |
| NCBI Full Name: | Ras-related protein Rab-5C |
| NCBI Synonym Full Names: | RAB5C, member RAS oncogene family |
| NCBI Official Symbol: | RAB5C |
| NCBI Official Synonym Symbols: | RABL; L1880; RAB5L; RAB5CL |
| NCBI Protein Information: | ras-related protein Rab-5C |
| UniProt Protein Name: | Ras-related protein Rab-5C |
| UniProt Synonym Protein Names: | L1880; RAB5L |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB5C |
| UniProt Entry Name: | RAB5C_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RAB5C antibody (CAB7342) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat kidney using RAB5C antibody (CAB7342) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human kidney using RAB5C antibody (CAB7342) at dilution of 1:100 (40x lens). |
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