Anti-RAB3IP Antibody (CAB12608)
- SKU:
- CAB12608
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RAB3IP Antibody |
| 抗体コード: | CAB12608 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human RAB3IP (NP_071901.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human RAB3IP (NP_071901.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAND PLEG FHEV NLAS PTSP DLLG VYES GTQE QTTS PSVI YRPH PSAL SSVP IQAN ALDV SELP TQPV YSSP RRLN CAEI SSIS FHVT DPAP CSTS GVTA GLTK LTTR KDNY NAER EFLQ GATI TEAC DGSD DIFG LSTD SLSR LRSP SV |
| 遺伝子ID: | 117177 |
| Uniprot: | Q96QF0 |
| セルラーロケーション: | Cell projection, Cytoplasm, Nucleus, cytoskeleton, lamellipodium |
| 計算された分子量: | 28kDa/33-53kDa |
| 観察された分子量: | 55kDa |
| 同義語: | RAB3IP, RABIN3, RABIN8 |
| バックグラウンド: |
| UniProt Protein Function: | RAB3IP: Guanine nucleotide exchange factor for RAB8A. Mediates the release of GDP from RAB8A but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Belongs to the SEC2 family. 8 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:GEF; GEF, Rab Chromosomal Location of Human Ortholog: 12q15 Cellular Component: cytosol; nucleus Molecular Function:protein binding; Rab guanyl-nucleotide exchange factor activity Biological Process: protein targeting to membrane |
| UniProt Code: | Q96QF0 |
| NCBI GenInfo Identifier: | 71152025 |
| NCBI Gene ID: | 117177 |
| NCBI Accession: | Q96QF0.1 |
| UniProt Secondary Accession: | Q96QF0,Q6PCE4, Q96A24, Q96QE6, Q96QE7, Q96QE8, Q96QE9 Q96QF1, Q9H673, B7WPJ6, |
| UniProt Related Accession: | Q96QF0 |
| Molecular Weight: | 53kDa |
| NCBI Full Name: | Rab-3A-interacting protein |
| NCBI Synonym Full Names: | RAB3A interacting protein |
| NCBI Official Symbol: | RAB3IP |
| NCBI Official Synonym Symbols: | RABIN3; RABIN8 |
| NCBI Protein Information: | rab-3A-interacting protein |
| UniProt Protein Name: | Rab-3A-interacting protein |
| UniProt Synonym Protein Names: | Rabin-3; SSX2-interacting protein |
| Protein Family: | Rab-3A-interacting protein |
| UniProt Gene Name: | RAB3IP |
 | Western blot analysis of extracts of 293T cells, using RAB3IP antibody (CAB12608) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 60s. |
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