Anti-RAB23 Antibody (CAB7979)
- SKU:
- CAB7979
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | RAB23 Rabbit Polyclonal Antibody |
抗体コード: | CAB7979 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-237 of human RAB23 (NP_057361.3). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, Mouse testis, Mouse brain, Mouse kidney, Mouse lung, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-237 of human RAB23 (NP_057361.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MLEE DMEV AIKM VVVG NGAV GKSS MIQR YCKG IFTK DYKK TIGV DFLE RQIQ VNDE DVRL MLWD TAGQ EEFD AITK AYYR GAQA CVLV FSTT DRES FEAV SSWR EKVV AEVG DIPT VLVQ NKID LLDD SCIK NEEA EALA KRLK LRFY RTSV KEDL NVNE VFKY LAEK YLQK LKQQ IAED PELT HSSS NKIG VFNT SGGS HSGQ NSGT LNGG DVIN LRPN KQRT KKNR NPFS SCSI P |
遺伝子ID: | 51715 |
Uniprot: | Q9ULC3 |
セルラーロケーション: | Cell membrane, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Endosome membrane, Lipid-anchor, autophagosome, phagosome, phagosome membrane |
計算された分子量: | 26kDa |
観察された分子量: | 27kDa |
同義語: | RAB23, HSPC137 |
バックグラウンド: | This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | RAB23: Defects in RAB23 are the cause of acrocephalopolysyndactyly type 2 (ACPS2). A syndrome characterized by craniosynostosis, polysyndactyly, obesity, and cardiac defects. Belongs to the small GTPase superfamily. Rab family. |
UniProt Protein Details: | Protein type:G protein, monomeric; G protein, monomeric, Rab; G protein Chromosomal Location of Human Ortholog: 6p11 Cellular Component: phagocytic vesicle membrane; cytoplasm; plasma membrane; endosome membrane; autophagic vacuole; phagocytic vesicle Molecular Function:GTPase activity; protein binding; GDP binding; GTP binding Biological Process: negative regulation of proteolysis; protein transport; spinal cord dorsal/ventral patterning; cellular defense response; cilium biogenesis; embryonic digit morphogenesis; Rab protein signal transduction; negative regulation of transcription factor import into nucleus; autophagic vacuole formation; regulation of smoothened signaling pathway Disease: Carpenter Syndrome 1 |
NCBI Summary: | This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
UniProt Code: | Q9ULC3 |
NCBI GenInfo Identifier: | 523425714 |
NCBI Gene ID: | 51715 |
NCBI Accession: | NP_001265595.1 |
UniProt Secondary Accession: | Q9ULC3,Q68DJ6, Q8NI06, Q9P023, B2R9I5, |
UniProt Related Accession: | Q9ULC3 |
Molecular Weight: | 26,659 Da |
NCBI Full Name: | ras-related protein Rab-23 |
NCBI Synonym Full Names: | RAB23, member RAS oncogene family |
NCBI Official Symbol: | RAB23 |
NCBI Official Synonym Symbols: | HSPC137 |
NCBI Protein Information: | ras-related protein Rab-23; RAB family small GTP binding protein RAB 23 |
UniProt Protein Name: | Ras-related protein Rab-23 |
Protein Family: | Ras-related protein |
UniProt Gene Name: | RAB23 |
UniProt Entry Name: | RAB23_HUMAN |
View AllClose