Anti-RAB14 Antibody (CAB12752)
- SKU:
- CAB12752
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
抗体名: | Anti-RAB14 Antibody |
抗体コード: | CAB12752 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 126-215 of human RAB14 (NP_057406.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | U-87MG, LO2 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 126-215 of human RAB14 (NP_057406.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | ADLE AQRD VTYE EAKQ FAEE NGLL FLEA SAKT GENV EDAF LEAA KKIY QNIQ DGSL DLNA AESG VQHK PSAP QGGR LTSE PQPQ REGC GC |
遺伝子ID: | 51552 |
Uniprot: | P61106 |
セルラーロケーション: | Cytoplasmic side, Cytoplasmic vesicle, Early endosome membrane, Golgi apparatus, Golgi apparatus membrane, Lipid-anchor, Recycling endosome, phagosome, phagosome membrane, trans-Golgi network membrane |
計算された分子量: | 23kDa |
観察された分子量: | 26kDa |
同義語: | RAB14, FBP, RAB-14 |
バックグラウンド: |
UniProt Protein Function: | RAB14: a protein of the GTPase superfamily, Rab family. May be involved in vesicular trafficking and neurotransmitter release. Localized to the inner face of the cell membrane by a lipid-anchor. |
UniProt Protein Details: | Protein type:G protein; G protein, monomeric; G protein, monomeric, Rab Chromosomal Location of Human Ortholog: 9q33.2 Cellular Component: cilium; cytoplasmic vesicle membrane; cytosol; early endosome; early endosome membrane; Golgi stack; intracellular; intracellular membrane-bound organelle; late endosome; lysosomal membrane; lysosome; nuclear envelope-endoplasmic reticulum network; perinuclear region of cytoplasm; phagocytic vesicle; plasma membrane; recycling endosome; recycling endosome membrane; rough endoplasmic reticulum; trans-Golgi network transport vesicle Molecular Function:GDP binding; GTP binding; GTPase activity; myosin V binding; protein binding Biological Process: embryonic development; endocytic recycling; fibroblast growth factor receptor signaling pathway; Golgi to endosome transport; neutrophil degranulation; phosphatidylinositol biosynthetic process; regulation of endocytosis; regulation of protein localization |
NCBI Summary: | RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]).[supplied by OMIM, Mar 2009] |
UniProt Code: | P61106 |
NCBI GenInfo Identifier: | 85700392 |
NCBI Gene ID: | 51552 |
NCBI Accession: | P61106.4 |
UniProt Secondary Accession: | P61106,P35287, Q5JVD4, Q6Q7K5, Q969L0, Q9UI11, B3KR31 |
UniProt Related Accession: | P61106 |
Molecular Weight: | 24kDa |
NCBI Full Name: | Ras-related protein Rab-14 |
NCBI Synonym Full Names: | RAB14, member RAS oncogene family |
NCBI Official Symbol: | RAB14 |
NCBI Official Synonym Symbols: | FBP; RAB-14 |
NCBI Protein Information: | ras-related protein Rab-14 |
UniProt Protein Name: | Ras-related protein Rab-14 |
Protein Family: | Ras-related protein |
UniProt Gene Name: | RAB14 |