Anti-RAB11FIP4 Antibody (CAB15914)
- SKU:
- CAB15914
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-RAB11FIP4 Antibody |
| 抗体コード: | CAB15914 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 338-637 of human RAB11FIP4 (NP_116321.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | U-87MG |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 338-637 of human RAB11FIP4 (NP_116321.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | NDIT EKVS FLEK KVTE LEND SLTN GDLK SKLK QENT QLVH RVHE LEEM VKDQ ETTA EQAL EEEA RRHR EAYG KLER EKAT EVEL LNAR VQQL EEEN TELR TTVT RLKS QTEK LDEE RQRM SDRL EDTS LRLK DEMD LYKR MMDK LRQN RLEF QKER EATQ ELIE DLRK ELEH LQMY KLDC ERPG RGRS ASSG LGEF NARA REVE LEHE VKRL KQEN YKLR DQND DLNG QILS LSLY EAKN LFAA QTKA QSLA AEID TASR DELM EALK EQEE INFR LRQY MDKI ILAI LDHN PSIL EIKH |
| 遺伝子ID: | 84440 |
| Uniprot: | Q86YS3 |
| セルラーロケーション: | Cleavage furrow, Cytoplasmic vesicle, Midbody, Peripheral membrane protein, Recycling endosome membrane |
| 計算された分子量: | 60kDa/71kDa |
| 観察された分子量: | 72kDa |
| 同義語: | RAB11FIP4, FIP4-Rab11, RAB11-FIP4 |
| バックグラウンド: | The protein encoded by this gene interacts with RAB11 and is thought to be involved in bringing recycling endosome membranes to the cleavage furrow in late cytokinesis. Hypoxic conditions can lead to an upregulation of the encoded protein and enhance the metastatic potential of hepatocellular carcinoma. |
| UniProt Protein Function: | Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6. |
| NCBI Summary: | The protein encoded by this gene interacts with RAB11 and is thought to be involved in bringing recycling endosome membranes to the cleavage furrow in late cytokinesis. Hypoxic conditions can lead to an upregulation of the encoded protein and enhance the metastatic potential of hepatocellular carcinoma. [provided by RefSeq, Oct 2016] |
| UniProt Code: | Q86YS3 |
| NCBI GenInfo Identifier: | 756140942 |
| NCBI Gene ID: | 84440 |
| NCBI Accession: | NP_001290471.2 |
| UniProt Secondary Accession: | Q86YS3,Q52LI1, Q8N829, Q8NDT7, Q969D8, |
| UniProt Related Accession: | Q86YS3 |
| Molecular Weight: | 72kDa |
| NCBI Full Name: | rab11 family-interacting protein 4 isoform 2 |
| NCBI Synonym Full Names: | RAB11 family interacting protein 4 |
| NCBI Official Symbol: | RAB11FIP4 |
| NCBI Official Synonym Symbols: | FIP4-Rab11; RAB11-FIP4 |
| NCBI Protein Information: | rab11 family-interacting protein 4 |
| UniProt Protein Name: | Rab11 family-interacting protein 4 |
| UniProt Synonym Protein Names: | Arfophilin-2 |
| Protein Family: | Rab11 family-interacting protein |
| UniProt Gene Name: | RAB11FIP4 |
 | Western blot analysis of extracts of U-87MG cells, using RAB11FIP4 antibody (CAB15914) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 15s. |