Anti-PTPRJ Antibody (CAB10169)
- SKU:
- CAB10169
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PTPRJ Antibody |
| 抗体コード: | CAB10169 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 140-370 of human PTPRJ (NP_002834.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:1000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Raji |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 140-370 of human PTPRJ (NP_002834.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | KSND TAAS EYKY VVKH KMEN EKTI TVVH QPWC NITG LRPA TSYV FSIT PGIG NETW GDPR VIKV ITEP IPVS DLRV ALTG VRKA ALSW SNGN GTAS CRVL LESI GSHE ELTQ DSRL QVNI SGLK PGVQ YNIN PYLL QSNK TKGD PLGT EGGL DASN TERS RAGS PTAP VHDE SLVG PVDP SSGQ QSRD TEVL LVGL EPGT RYNA TVYS QAAN GTEG QPQA IEFR TNAI QVF |
| 遺伝子ID: | 5795 |
| Uniprot: | Q12913 |
| セルラーロケーション: | Cell junction, Cell membrane, Cell projection, Single-pass type I membrane protein, ruffle membrane |
| 計算された分子量: | 57kDa/145kDa |
| 観察された分子量: | 260kDa |
| 同義語: | PTPRJ, CD148, DEP1, HPTPeta, R-PTP-ETA, SCC1 |
| バックグラウンド: | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. |
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| UniProt Code: | Q12913 |
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| UniProt Secondary Accession: | Q12913 |
| UniProt Related Accession: | Q12913 |
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 | Western blot analysis of extracts of Raji cells, using PTPRJ antibody (CAB10169) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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