Anti-PTPRG Antibody (CAB14253)
- SKU:
- CAB14253
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PTPRG Antibody |
| 抗体コード: | CAB14253 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-450 of human PTPRG (NP_002832.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, 293T, Mouse kidney, Mouse heart, Mouse liver, Rat spleen |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-450 of human PTPRG (NP_002832.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | YRYT GSLT TPPC SEIV EWIV FRRP VPIS YHQL EAFY SIFT TEQQ DHVK SVEY LRNN FRPQ QRLH DRVV SKSA VRDS WNHD MTDF LENP LGTE ASKV CSSP PIHM KVQP LNQT ALQV SWSQ PETI YHPP IMNY MISY SWTK NEDE KEKT FTKD SDKD LKAT ISHV SPDS LYLF RVQA VCRN DMRS DFSQ TMLF QANT TRIF Q |
| 遺伝子ID: | 5793 |
| Uniprot: | P23470 |
| セルラーロケーション: | Membrane, Single-pass type I membrane protein |
| 計算された分子量: | 158kDa/162kDa |
| 観察された分子量: | 140-162kDa |
| 同義語: | PTPRG, HPTPG, PTPG, R-PTP-GAMMA, RPTPG |
| バックグラウンド: | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. |
| UniProt Protein Function: | PTPRG: Possesses tyrosine phosphatase activity. Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.1.3.48; Phosphatase; Receptor protein phosphatase, tyrosine; Membrane protein, integral; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 3p21-p14 Cellular Component: integral to plasma membrane Molecular Function:identical protein binding; protein binding; protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase activity Biological Process: transmembrane receptor protein tyrosine kinase signaling pathway |
| NCBI Summary: | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P23470 |
| NCBI GenInfo Identifier: | 229463033 |
| NCBI Gene ID: | 5793 |
| NCBI Accession: | P23470.4 |
| UniProt Secondary Accession: | P23470,Q15623, Q59EE0, Q68DU5, B2RU12, B7ZLX5, |
| UniProt Related Accession: | P23470 |
| Molecular Weight: | 158,771 Da |
| NCBI Full Name: | Receptor-type tyrosine-protein phosphatase gamma |
| NCBI Synonym Full Names: | protein tyrosine phosphatase, receptor type G |
| NCBI Official Symbol: | PTPRG |
| NCBI Official Synonym Symbols: | PTPG; HPTPG; RPTPG; R-PTP-GAMMA |
| NCBI Protein Information: | receptor-type tyrosine-protein phosphatase gamma |
| UniProt Protein Name: | Receptor-type tyrosine-protein phosphatase gamma |
| Protein Family: | Receptor-type tyrosine-protein phosphatase |
| UniProt Gene Name: | PTPRG |
| UniProt Entry Name: | PTPRG_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PTPRG antibody (CAB14253) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
View AllClose