Anti-PTP4A1 Antibody (CAB12360)
- SKU:
- CAB12360
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-PTP4A1 Antibody |
| 抗体コード: | CAB12360 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human PTP4A1 (NP_003454.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, Mouse liver, Rat skeletal muscle, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human PTP4A1 (NP_003454.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MARM NRPA PVEV TYKN MRFL ITHN PTNA TLNK FIEE LKKY GVTT IVRV CEAT YDTT LVEK EGIH VLDW PFDD GAPP SNQI VDDW LSLV KIKF REEP GCCI AVHC VAGL GRAP VLVA LALI EGGM KYED AVQF IRQK RRGA FNSK QLLY LEKY RPKM RLRF KDSN GHRN NCCI Q |
| 遺伝子ID: | 7803 |
| Uniprot: | Q93096 |
| セルラーロケーション: | Cell membrane, Cytoplasm, Early endosome, Endoplasmic reticulum, cytoskeleton, spindle |
| 計算された分子量: | 19kDa |
| 観察された分子量: | 20kDa |
| 同義語: | PTP4A1, HH72, PRL-1, PRL1, PTP(CAAX1), PTPCAAX1 |
| バックグラウンド: | This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. |
| UniProt Protein Function: | PTP4A1: Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. Belongs to the protein-tyrosine phosphatase family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor) Chromosomal Location of Human Ortholog: 6q12 Cellular Component: cytoplasm; internal side of plasma membrane; nucleus Molecular Function:protein tyrosine phosphatase activity Biological Process: positive regulation of cell migration |
| NCBI Summary: | This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. [provided by RefSeq, Jun 2013] |
| UniProt Code: | Q93096 |
| NCBI GenInfo Identifier: | 68566217 |
| NCBI Gene ID: | 7803 |
| NCBI Accession: | Q93096.2 |
| UniProt Secondary Accession: | Q93096,O00648, Q49A54, B2R6C8, |
| UniProt Related Accession: | Q93096 |
| Molecular Weight: | 19,815 Da |
| NCBI Full Name: | Protein tyrosine phosphatase type IVA 1 |
| NCBI Synonym Full Names: | protein tyrosine phosphatase type IVA, member 1 |
| NCBI Official Symbol: | PTP4A1 |
| NCBI Official Synonym Symbols: | HH72; PRL1; PRL-1; PTPCAAX1; PTP(CAAX1) |
| NCBI Protein Information: | protein tyrosine phosphatase type IVA 1 |
| UniProt Protein Name: | Protein tyrosine phosphatase type IVA 1 |
| UniProt Synonym Protein Names: | PTP(CAAXI); Protein-tyrosine phosphatase 4a1; Protein-tyrosine phosphatase of regenerating liver 1; PRL-1 |
| Protein Family: | Protein tyrosine phosphatase |
| UniProt Gene Name: | PTP4A1 |
| UniProt Entry Name: | TP4A1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PTP4A1 antibody (CAB12360) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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