Anti-PTGIR Antibody (CAB1849)
- SKU:
- CAB1849
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-PTGIR Antibody |
抗体コード: | CAB1849 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 207-386 of human PTGIR (NP_000951.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse eye, Mouse liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 207-386 of human PTGIR (NP_000951.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | TLSL CRMY RQQK RHQG SLGP RPRT GEDE VDHL ILLA LMTV VMAV CSLP LTIR CFTQ AVAP DSSS EMGD LLAF RFYA FNPI LDPW VFIL FRKA VFQR LKLW VCCL CLGP AHGD SQTP LSQL ASGR RDPR APSA PVGK EGSC VPLS AWGE GQVE PLPP TQQS SGSA VGTS SKAE ASVA CSLC |
遺伝子ID: | 5739 |
Uniprot: | P43119 |
セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
計算された分子量: | 40kDa |
観察された分子量: | 41kDa |
同義語: | PTGIR, IP, PRIPR |
バックグラウンド: | The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. |
UniProt Protein Function: | PTGIR: Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: integral to plasma membrane; plasma membrane; cytosol Molecular Function:G-protein coupled receptor activity; guanyl-nucleotide exchange factor activity Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; cell-cell signaling; negative regulation of smooth muscle cell proliferation; positive regulation of cAMP biosynthetic process; response to lipopolysaccharide; blood coagulation; G-protein signaling, adenylate cyclase activating pathway; positive regulation of GTPase activity |
NCBI Summary: | The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008] |
UniProt Code: | P43119 |
NCBI GenInfo Identifier: | 1172500 |
NCBI Gene ID: | 5739 |
NCBI Accession: | P43119.1 |
UniProt Related Accession: | P43119 |
Molecular Weight: | Calculated: 40kDaObserved: 41kDa |
NCBI Full Name: | Prostacyclin receptor |
NCBI Synonym Full Names: | prostaglandin I2 (prostacyclin) receptor (IP) |
NCBI Official Symbol: | PTGIR |
NCBI Official Synonym Symbols: | IP; PRIPR |
NCBI Protein Information: | prostacyclin receptor; PGI receptor; PGI2 receptor; prostanoid IP receptor; prostaglandin I2 receptor |
UniProt Protein Name: | Prostacyclin receptor |
UniProt Synonym Protein Names: | Prostaglandin I2 receptor; PGI receptor; PGI2 receptor; Prostanoid IP receptor |
Protein Family: | Prostacyclin receptor |
UniProt Gene Name: | PTGIR |
UniProt Entry Name: | PI2R_HUMAN |
View AllClose