Anti-PTGFR Antibody (CAB15088)
- SKU:
- CAB15088
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PTGFR Antibody |
| 抗体コード: | CAB15088 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PTGFR (NP_000950.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | mouse liver, mouse brain, rat brain |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PTGFR (NP_000950.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | ILMK AYQR FRQK SKAS FLLL ASGL VITD FFGH LING AIAV FVYA SDKE WIRF DQSN VLCS IFGI CMVF SGLC PLLL GSVM AIER CIGV TKPI FHST KITS K |
| 遺伝子ID: | 5737 |
| Uniprot: | P43088 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 29kDa/30kDa/32kDa/33kDa/40kDa |
| 観察された分子量: | 40kDa |
| 同義語: | PTGFR, FP |
| バックグラウンド: | The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | PTGFR: Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Receptor, GPCR; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 1p31.1 Cellular Component: cytoplasm; extracellular region; integral to plasma membrane; plasma membrane Molecular Function:prostaglandin F receptor activity Biological Process: parturition; positive regulation of cell proliferation |
| NCBI Summary: | The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P43088 |
| NCBI GenInfo Identifier: | 1172442 |
| NCBI Gene ID: | 5737 |
| NCBI Accession: | P43088.1 |
| UniProt Secondary Accession: | P43088,Q2KHP3, Q6RYQ6, Q9P1X4, A8K9Y0, |
| UniProt Related Accession: | P43088 |
| Molecular Weight: | 30,766 Da |
| NCBI Full Name: | Prostaglandin F2-alpha receptor |
| NCBI Synonym Full Names: | prostaglandin F receptor |
| NCBI Official Symbol: | PTGFR |
| NCBI Official Synonym Symbols: | FP |
| NCBI Protein Information: | prostaglandin F2-alpha receptor |
| UniProt Protein Name: | Prostaglandin F2-alpha receptor |
| UniProt Synonym Protein Names: | Prostanoid FP receptor |
| Protein Family: | Prostaglandin F2-alpha receptor |
| UniProt Gene Name: | PTGFR |
| UniProt Entry Name: | PF2R_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PTGFR antibody (CAB15088) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
View AllClose