Anti-PTGER2 Antibody (CAB2914)
- SKU:
- CAB2914
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PTGER2 Antibody |
| 抗体コード: | CAB2914 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide of human PTGER2 |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:100 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | K-562, SW480, 22Rv1, OVCAR3 |
| 免疫原: | A synthetic peptide of human PTGER2 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 5732 |
| Uniprot: | P43116 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 39kDa |
| 観察された分子量: | 40kDa |
| 同義語: | PTGER2, EP2 |
| バックグラウンド: | This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. |
| UniProt Protein Function: | PTGER2: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral Chromosomal Location of Human Ortholog: 14q22 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:prostaglandin E receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase activating pathway; regulation of cell proliferation; response to lipopolysaccharide; response to progesterone stimulus Disease: Asthma, Nasal Polyps, And Aspirin Intolerance |
| NCBI Summary: | This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009] |
| UniProt Code: | P43116 |
| NCBI GenInfo Identifier: | 38258920 |
| NCBI Gene ID: | 5732 |
| NCBI Accession: | P43116.2 |
| UniProt Secondary Accession: | P43116,Q52LG8, D3DSC0, |
| UniProt Related Accession: | P43116 |
| Molecular Weight: | 39,761 Da |
| NCBI Full Name: | Prostaglandin E2 receptor EP2 subtype |
| NCBI Synonym Full Names: | prostaglandin E receptor 2 |
| NCBI Official Symbol: | PTGER2 |
| NCBI Official Synonym Symbols: | EP2 |
| NCBI Protein Information: | prostaglandin E2 receptor EP2 subtype |
| UniProt Protein Name: | Prostaglandin E2 receptor EP2 subtype |
| UniProt Synonym Protein Names: | Prostanoid EP2 receptor |
| Protein Family: | Prostaglandin E2 receptor |
| UniProt Gene Name: | PTGER2 |
| UniProt Entry Name: | PE2R2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PTGER2 antibody (CAB2914) at 1:200 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat lung using PTGER2 Antibody (CAB2914) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse lung using PTGER2 Antibody (CAB2914) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of HeLa cells using PTGER2 antibody (CAB2914). |
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