UniProt Protein Function: | Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. |
UniProt Code: | O75475 |
NCBI GenInfo Identifier: | 68565853 |
NCBI Gene ID: | 11168 |
NCBI Accession: | O75475.1 |
UniProt Secondary Accession: | O75475,O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6 D3DRI9, |
UniProt Related Accession: | O75475 |
Molecular Weight: | 76; 51; 45 kDa |
NCBI Full Name: | PC4 and SFRS1-interacting protein |
NCBI Synonym Full Names: | PC4 and SFRS1 interacting protein 1 |
NCBI Official Symbol: | PSIP1 |
NCBI Official Synonym Symbols: | p52; p75; PAIP; DFS70; LEDGF; PSIP2 |
NCBI Protein Information: | PC4 and SFRS1-interacting protein |
UniProt Protein Name: | PC4 and SFRS1-interacting protein |
UniProt Synonym Protein Names: | CLL-associated antigen KW-7; Dense fine speckles 70 kDa protein; DFS 70; Lens epithelium-derived growth factor; Transcriptional coactivator p75/p52 |
Protein Family: | PC4 and SFRS1-interacting protein |
UniProt Gene Name: | PSIP1 |