Anti-PRSS21 Antibody (CAB16100)
- SKU:
- CAB16100
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PRSS21 Antibody |
| 抗体コード: | CAB16100 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-220 of human PRSS21 (NP_006790.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse testis, Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-220 of human PRSS21 (NP_006790.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | TKHI QPIC LQAS TFEF ENRT DCWV TGWG YIKE DEAL PSPH TLQE VQVA IINN SMCN HLFL KYSF RKDI FGD |
| 遺伝子ID: | 10942 |
| Uniprot: | Q9Y6M0 |
| セルラーロケーション: | Cell membrane, GPI-anchor, Lipid-anchor |
| 計算された分子量: | 33kDa/34kDa |
| 観察された分子量: | 36kDa |
| 同義語: | PRSS21, ESP-1, ESP1, TEST1, TESTISIN, testisin |
| バックグラウンド: | This gene encodes a cell-surface anchored serine protease, which is a member of the trypsin family of serine proteases. The encoded protein is predicted to be active on peptide linkages involving the carboxyl group of lysine or arginine. The encoded protein localizes to the cytoplasm and the plasma membrane of premeiotic testicular germ cells and may be involved in progression of testicular tumors of germ cell origin. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| UniProt Protein Function: | PRSS21: Could regulate proteolytic events associated with testicular germ cell maturation. Belongs to the peptidase S1 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Protease; EC 3.4.21.-; Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: cytoplasm; membrane Molecular Function:protein binding; serine-type peptidase activity |
| NCBI Summary: | This gene encodes a cell-surface anchored serine protease, which is a member of the trypsin family of serine proteases. The encoded protein is predicted to be active on peptide linkages involving the carboxyl group of lysine or arginine. The encoded protein localizes to the cytoplasm and the plasma membrane of premeiotic testicular germ cells and may be involved in progression of testicular tumors of germ cell origin. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
| UniProt Code: | Q9Y6M0 |
| NCBI GenInfo Identifier: | 13633973 |
| NCBI Gene ID: | 10942 |
| NCBI Accession: | Q9Y6M0.1 |
| UniProt Secondary Accession: | Q9Y6M0,Q9NS34, Q9P2V6, |
| UniProt Related Accession: | Q9Y6M0 |
| Molecular Weight: | 33,562 Da |
| NCBI Full Name: | Testisin |
| NCBI Synonym Full Names: | protease, serine 21 |
| NCBI Official Symbol: | PRSS21 |
| NCBI Official Synonym Symbols: | ESP1; ESP-1; TEST1; TESTISIN |
| NCBI Protein Information: | testisin |
| UniProt Protein Name: | Testisin |
| UniProt Synonym Protein Names: | Eosinophil serine protease 1; ESP-1; Serine protease 21 |
| Protein Family: | Testisin |
| UniProt Gene Name: | PRSS21 |
| UniProt Entry Name: | TEST_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PRSS21 antibody (CAB16100) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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