Anti-Proteinase 3/PR3 Antibody (CAB19748)
- SKU:
- CAB19748
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ACPA
- Synonyms:
- AGP7
- Synonyms:
- C-ANCA
- Synonyms:
- CANCA
- Synonyms:
- MBN
- Synonyms:
- MBT
- Synonyms:
- NP-4
- Synonyms:
- NP4
- Synonyms:
- P29
- Synonyms:
- PR-3
- Synonyms:
- PR3
Frequently bought together:
Description
| I抗体名: | Proteinase 3/PR3 Rabbit mAb |
| 抗体コード: | CAB19748 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP-4, NP4, P29, PR-3, PR3 |
| 申し込み: | WB, IF |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human Proteinase 3/PR3 |
| 申し込み: | WB, IF |
| 推奨される希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Mouse liver |
| 免疫原: | A synthesized peptide derived from human Proteinase 3/PR3 |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 5657 |
| Uniprot: | P24158 |
| 計算された分子量: | 27kDa |
| 観察された分子量: | 28KDa |
| UniProt Protein Function: | PRTN3: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Belongs to the peptidase S1 family. Elastase subfamily. |
| UniProt Protein Details: | Protein type:EC 3.4.21.76; Cell cycle regulation; Protease Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: cytosol; extracellular matrix; extracellular space; plasma membrane Molecular Function:enzyme binding; serine-type endopeptidase activity; serine-type peptidase activity Biological Process: blood coagulation; negative regulation of phagocytosis; positive regulation of cell proliferation |
| UniProt Code: | P24158 |
| NCBI GenInfo Identifier: | 6174926 |
| NCBI Gene ID: | 5657 |
| NCBI Accession: | P24158.3 |
| UniProt Secondary Accession: | P24158,P15637, P18078, Q4VB08, Q4VB09, Q6LBM7, Q6LBN2 Q9UD25, Q9UQD8, |
| UniProt Related Accession: | P24158 |
| Molecular Weight: | 27,807 Da |
| NCBI Full Name: | Myeloblastin |
| NCBI Synonym Full Names: | proteinase 3 |
| NCBI Official Symbol: | PRTN3 |
| NCBI Official Synonym Symbols: | MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA |
| NCBI Protein Information: | myeloblastin |
| UniProt Protein Name: | Myeloblastin |
| UniProt Synonym Protein Names: | AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigen |
| Protein Family: | Myeloblastin |
| UniProt Gene Name: | PRTN3 |
| UniProt Entry Name: | PRTN3_HUMAN |