Anti-Prostatic Acid Phosphatase (ACPP) Antibody (CAB4138)
- SKU:
- CAB4138
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- 5'-NT
- Synonyms:
- ACP-3
- Synonyms:
- ACP3
Description
| 抗体名: | Prostatic Acid Phosphatase (ACPP) Rabbit mAb |
| 抗体コード: | CAB4138 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | 5'-NT, ACP-3, ACP3 |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human Prostatic Acid Phosphatase (ACPP) (PAP/ACPP) |
| 申し込み: | WB |
| 推奨される希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse liver, Rat liver |
| 免疫原: | A synthesized peptide derived from human Prostatic Acid Phosphatase (ACPP) (PAP/ACPP) |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 55 |
| Uniprot: | P15309 |
| 計算された分子量: | 50kDa |
| 観察された分子量: | 45KDa |
| UniProt Protein Function: | ACPP: A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Belongs to the histidine acid phosphatase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.1.3.2; Cofactor and Vitamin Metabolism - riboflavin; Phosphatase; EC 3.1.3.5; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 3q22.1 Cellular Component: multivesicular body; extracellular space; Golgi cisterna; apical part of cell; lysosomal membrane; plasma membrane; integral to membrane; vesicle membrane; intracellular; nucleus; secretory granule; filopodium Molecular Function:5'-nucleotidase activity; choline binding; identical protein binding; acid phosphatase activity; protein homodimerization activity; phosphoric monoester hydrolase activity; thiamin phosphate phosphatase activity Biological Process: thiamin metabolic process; dephosphorylation; positive regulation of adenosine receptor signaling pathway; nucleotide metabolic process; regulation of sensory perception of pain; adenosine metabolic process; purine base metabolic process |
| NCBI Summary: | This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008] |
| UniProt Code: | P15309 |
| NCBI GenInfo Identifier: | 130730 |
| NCBI Gene ID: | 55 |
| NCBI Accession: | P15309.3 |
| UniProt Related Accession: | P15309 |
| Molecular Weight: | |
| NCBI Full Name: | Prostatic acid phosphatase |
| NCBI Synonym Full Names: | acid phosphatase, prostate |
| NCBI Official Symbol: | ACPP |
| NCBI Official Synonym Symbols: | ACP3; 5'-NT; ACP-3 |
| NCBI Protein Information: | prostatic acid phosphatase |
| UniProt Protein Name: | Prostatic acid phosphatase |
| UniProt Synonym Protein Names: | 5'-nucleotidase (EC:3.1.3.5); 5'-NT; Ecto-5'-nucleotidase; Thiamine monophosphatase; TMPase |
| UniProt Gene Name: | ACPP |
| UniProt Entry Name: | PPAP_HUMAN |