Anti-PROCR Antibody (CAB5763)
- SKU:
- CAB5763
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
| 抗体名: | Anti-PROCR Antibody |
| 抗体コード: | CAB5763 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-210 of human PROCR (NP_006395.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | MCF7, HepG2, HeLa, 293T, Mouse kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-210 of human PROCR (NP_006395.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SQDA SDGL QRLH MLQI SYFR DPYH VWYQ GNAS LGGH LTHV LEGP DTNT TIIQ LQPL QEPE SWAR TQSG LQSY LLQF HGLV RLVH QERT LAFP LTIR CFLG CELP PEGS RAHV FFEV AVNG SSFV SFRP ERAL WQAD TQVT SGVV TFTL QQLN AYNR TRYE LREF LEDT CVQY VQKH ISAE NTKG SQTS RSYT S |
| 遺伝子ID: | 10544 |
| Uniprot: | Q9UNN8 |
| セルラーロケーション: | Membrane, Single-pass type I membrane protein |
| 計算された分子量: | 26kDa |
| 観察された分子量: | 45kDa |
| 同義語: | PROCR, CCCA, CCD41, EPCR, h-PROCR |
| バックグラウンド: | The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. |
| UniProt Protein Function: | Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation. |
| NCBI Summary: | The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9UNN8 |
| NCBI GenInfo Identifier: | 13626550 |
| NCBI Gene ID: | 10544 |
| NCBI Accession: | Q9UNN8.1 |
| UniProt Secondary Accession: | Q9UNN8,Q14218, Q6IB56, Q96CB3, Q9ULX1, B2RC04, |
| UniProt Related Accession: | Q9UNN8 |
| Molecular Weight: | 26,671 Da |
| NCBI Full Name: | Endothelial protein C receptor |
| NCBI Synonym Full Names: | protein C receptor |
| NCBI Official Symbol: | PROCR |
| NCBI Official Synonym Symbols: | CCCA; EPCR; CCD41 |
| NCBI Protein Information: | endothelial protein C receptor |
| UniProt Protein Name: | Endothelial protein C receptor |
| UniProt Synonym Protein Names: | Activated protein C receptor; APC receptor; Endothelial cell protein C receptor; CD_antigen: CD201 |
| Protein Family: | Endothelial protein C receptor |
| UniProt Gene Name: | PROCR |
 | Western blot analysis of extracts of various cell lines, using PROCR antibody (CAB5763) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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