Anti-PRM2 Antibody (CAB6704)
- SKU:
- CAB6704
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-PRM2 Antibody |
| 抗体コード: | CAB6704 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human PRM2 (NP_002753.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human PRM2 (NP_002753.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MVRY RVRS LSER SHEV YRQQ LHGQ EQGH HGQE EQGL SPEH VEVY ERTH GQSH YRRR HCSR RRLH RIHR RQHR SCRR RKRR SCRH RRRH RRGC RTRK RTCR RH |
| 遺伝子ID: | 5620 |
| Uniprot: | P04554 |
| セルラーロケーション: | Chromosome, Nucleus |
| 計算された分子量: | 13kDa/17kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | PRM2, CT94.2 |
| バックグラウンド: | Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis, and are the major DNA-binding proteins in the nucleus of sperm in many vertebrates. They package the sperm DNA into a highly condensed complex in a volume less than 5% of a somatic cell nucleus. Many mammalian species have only one protamine (protamine 1); however, a few species, including human and mouse, have two. This gene encodes protamine 2, which is cleaved to give rise to a family of protamine 2 peptides. Alternatively spliced transcript variants have also been found for this gene. |
| UniProt Protein Function: | PRM2: Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. Belongs to the protamine P2 family. |
| UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA); DNA-binding Chromosomal Location of Human Ortholog: 16p13.13 Cellular Component: nucleoplasm; nucleosome; nucleus Molecular Function:cadmium ion binding; DNA binding; zinc ion binding Biological Process: chromosome condensation; DNA packaging; multicellular organism development; nucleus organization; spermatid development; spermatogenesis |
| UniProt Code: | P04554 |
| NCBI GenInfo Identifier: | 886877 |
| NCBI Gene ID: | |
| NCBI Accession: | CAA87066.1 |
| UniProt Secondary Accession: | P04554,Q6ZMM0, |
| Molecular Weight: | 17,106 Da |
| NCBI Full Name: | protamine 2 |
| UniProt Protein Name: | Protamine-2 |
| UniProt Synonym Protein Names: | Sperm histone P2; Sperm protamine P2 |
| UniProt Gene Name: | PRM2 |
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