Anti-PRKACG Antibody (CAB14552)
- SKU:
- CAB14552
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| 抗体名: | Anti-PRKACG Antibody |
| 抗体コード: | CAB14552 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PRKACG (NP_002723.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | 293T, SKOV3 |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PRKACG (NP_002723.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MGNA PAKK DTEQ EESV NEFL AKAR GDFL YRWG NPAQ NTAS SDQF ERLR TLGM GSFG RVML VRHQ ETGG HYAM KILN KQKV VKMK QVEH ILNE KRIL QAID |
| 遺伝子ID: | 5568 |
| Uniprot: | P22612 |
| セルラーロケーション: | |
| 計算された分子量: | 40kDa |
| 観察された分子量: | 42kDa |
| 同義語: | PRKACG, BDPLT19, KAPG, PKACg |
| バックグラウンド: | Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. |
| UniProt Protein Function: | PKACG: Phosphorylates a large number of substrates in the cytoplasm and the nucleus. A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript. Activated by cAMP. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. |
| UniProt Protein Details: | Protein type:Protein kinase, AGC; EC 2.7.11.11; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; AGC group; PKA family Chromosomal Location of Human Ortholog: 9q13 Cellular Component: cytosol Molecular Function:cAMP-dependent protein kinase activity; ATP binding Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; water transport; activation of protein kinase A; male gonad development; glucose metabolic process; pathogenesis; signal transduction; protein amino acid phosphorylation; gluconeogenesis; phospholipase C activation; triacylglycerol catabolic process; carbohydrate metabolic process; energy reserve metabolic process; innate immune response; renal water homeostasis; spermatogenesis; blood coagulation; regulation of insulin secretion; transmembrane transport Disease: Mental Retardation, Autosomal Dominant 31 |
| NCBI Summary: | Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P22612 |
| NCBI GenInfo Identifier: | 207029159 |
| NCBI Gene ID: | 5568 |
| NCBI Accession: | NP_002723.2 |
| UniProt Secondary Accession: | P22612,O60850, Q5VZ02, Q86YI1, |
| UniProt Related Accession: | P22612 |
| Molecular Weight: | 65.0 kDa |
| NCBI Full Name: | Homo sapiens protein kinase, cAMP-dependent, catalytic, gamma (PRKACG), mRNA |
| NCBI Synonym Full Names: | protein kinase, cAMP-dependent, catalytic, gamma |
| NCBI Official Symbol: | PRKACG |
| NCBI Official Synonym Symbols: | KAPG; PKACg; BDPLT19 |
| NCBI Protein Information: | cAMP-dependent protein kinase catalytic subunit gamma |
| UniProt Protein Name: | cAMP-dependent protein kinase catalytic subunit gamma |
| Protein Family: | Protein lysine acetyltransferase |
| UniProt Gene Name: | PRKACG |
| UniProt Entry Name: | KAPCG_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PRKACG antibody (CAB14552) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |