Anti-PREB Antibody (CAB14347)
- SKU:
- CAB14347
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PREB Antibody |
| 抗体コード: | CAB14347 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 13-202 of human PREB (NP_037520.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | U-87MG, A-549, HeLa, LO2, Mouse heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 13-202 of human PREB (NP_037520.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PFPL YALQ VDPS TGLL IAAG GGGA AKTG IKNG VHFL QLEL INGR LSAS LLHS HDTE TRAT MNLA LAGD ILAA GQDA HCQL LRFQ AHQQ QGNK AEKA GSKE QGPR QRKG AAPA EKKC GAET QHEG LELR VENL QAVQ TDFS SDPL QKVV CFNH DNTL LATG GTDG YVRV WKVP SLEK VLEF KAHE GEIE DL |
| 遺伝子ID: | 10113 |
| Uniprot: | Q9HCU5 |
| セルラーロケーション: | Endoplasmic reticulum membrane, Nucleus, Single-pass membrane protein |
| 計算された分子量: | 45kDa |
| 観察された分子量: | 45kDa |
| 同義語: | PREB, SEC12 |
| バックグラウンド: | This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand. |
| UniProt Protein Function: | Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitement of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER. |
| NCBI Summary: | This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9HCU5 |
| NCBI GenInfo Identifier: | 1060099391 |
| NCBI Gene ID: | 10113 |
| NCBI Accession: | NP_001317414.1 |
| UniProt Secondary Accession: | Q9HCU5,Q53SZ8, Q9UH94, |
| UniProt Related Accession: | Q9HCU5 |
| Molecular Weight: | Calculated: 45kDaObserved: 50kDa |
| NCBI Full Name: | prolactin regulatory element-binding protein isoform 3 |
| NCBI Synonym Full Names: | prolactin regulatory element binding |
| NCBI Official Symbol: | PREB |
| NCBI Official Synonym Symbols: | SEC12 |
| NCBI Protein Information: | prolactin regulatory element-binding protein |
| UniProt Protein Name: | Prolactin regulatory element-binding protein |
| UniProt Synonym Protein Names: | Mammalian guanine nucleotide exchange factor mSec12 |
| Protein Family: | Preblooming protein |
| UniProt Gene Name: | PREB |
 | Western blot analysis of extracts of various cell lines, using PREB antibody (CAB14347) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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