Anti-PRDX4 Antibody (CAB18308)
- SKU:
- CAB18308
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PRDX4 Antibody |
| 抗体コード: | CAB18308 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human PRDX4. |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HepG2, U-251MG, BxPC-3, Mouse brain, Rat brain, Rat liver |
| 免疫原: | Recombinant protein of human PRDX4. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 10549 |
| Uniprot: | Q13162 |
| セルラーロケーション: | Cytoplasm, Secreted |
| 計算された分子量: | 30kDa |
| 観察された分子量: | 30kDa |
 | Western blot - PRDX4 Rabbit pAb (CAB18308) |
| 同義語: | PRDX4, AOE37-2, AOE372, HEL-S-97n, PRX-4 |
| バックグラウンド: | The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. |
| UniProt Protein Function: | PRDX4: Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. Belongs to the AhpC/TSA family. |
| UniProt Protein Details: | Protein type:Oxidoreductase; EC 1.11.1.15; Secreted; Mitochondrial; Secreted, signal peptide Chromosomal Location of Human Ortholog: Xp22.11 Cellular Component: cytosol; extracellular space; mitochondrion; nucleus; smooth endoplasmic reticulum Molecular Function:protein binding; protein homodimerization activity; thioredoxin peroxidase activity Biological Process: 4-hydroxyproline metabolic process; cell redox homeostasis; extracellular matrix organization and biogenesis; I-kappaB phosphorylation; male gonad development; protein maturation via protein folding; spermatogenesis |
| NCBI Summary: | The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q13162 |
| NCBI GenInfo Identifier: | 3024727 |
| NCBI Gene ID: | 10549 |
| NCBI Accession: | Q13162.1 |
| UniProt Secondary Accession: | Q13162,Q6FHT3, |
| UniProt Related Accession: | Q13162 |
| Molecular Weight: | |
| NCBI Full Name: | Peroxiredoxin-4 |
| NCBI Synonym Full Names: | peroxiredoxin 4 |
| NCBI Official Symbol: | PRDX4 |
| NCBI Official Synonym Symbols: | PRX-4; AOE372; AOE37-2; HEL-S-97n |
| NCBI Protein Information: | peroxiredoxin-4 |
| UniProt Protein Name: | Peroxiredoxin-4 |
| UniProt Synonym Protein Names: | Antioxidant enzyme AOE372; AOE37-2; Peroxiredoxin IV; Prx-IV; Thioredoxin peroxidase AO372; Thioredoxin-dependent peroxide reductase A0372 |
| Protein Family: | Peroxiredoxin |
| UniProt Gene Name: | PRDX4 |
| UniProt Entry Name: | PRDX4_HUMAN |