Anti-PPP2R5A Antibody (CAB15706)
- SKU:
- CAB15706
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PPP2R5A Antibody |
| 抗体コード: | CAB15706 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-130 of human PPP2R5A (NP_006234.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | MCF7, U-87MG, LO2, HeLa |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-130 of human PPP2R5A (NP_006234.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | QAEL HPLP QLKD ATSN EQQE LFCQ KLQQ CCIL FDFM DSVS DLKS KEIK RATL NELV EYVS TNRG VIVE SAYS DIVK MISA N |
| 遺伝子ID: | 5525 |
| Uniprot: | Q15172 |
| セルラーロケーション: | Chromosome, Cytoplasm, Nucleus, centromere |
| 計算された分子量: | 50kDa/56kDa |
| 観察された分子量: | 56kDa |
| 同義語: | PPP2R5A, B56A, PR61A, B56alpha |
| バックグラウンド: | The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene. |
| UniProt Protein Function: | PPP2R5A: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Belongs to the phosphatase 2A regulatory subunit B56 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Protein phosphatase, regulatory subunit; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 1q32.2-q32.3 Cellular Component: protein phosphatase type 2A complex; membrane; cytoplasm; M band; Z disc; nucleus; chromosome, pericentric region Molecular Function:protein binding; protein phosphatase type 2A regulator activity; kinase binding Biological Process: signal transduction; positive regulation of protein amino acid dephosphorylation |
| NCBI Summary: | The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010] |
| UniProt Code: | Q15172 |
| NCBI GenInfo Identifier: | 7387496 |
| NCBI Gene ID: | 5525 |
| NCBI Accession: | Q15172.1 |
| UniProt Secondary Accession: | Q15172,Q2NL72, Q5VVB2, Q8TBI9, B2R6D2, B7Z7L2, D3DT99 |
| UniProt Related Accession: | Q15172 |
| Molecular Weight: | 486 |
| NCBI Full Name: | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform |
| NCBI Synonym Full Names: | protein phosphatase 2, regulatory subunit B', alpha |
| NCBI Official Symbol: | PPP2R5A |
| NCBI Official Synonym Symbols: | B56A; PR61A |
| NCBI Protein Information: | serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; PR61alpha; PP2A B subunit isoform B'-alpha; PP2A B subunit isoform R5-alpha; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform PR61-alpha; PP2A, B subunit, B' alpha isoform; PP2A, B subunit, R5 alpha isoform; PP2A, B subunit, B56 alpha isoform; PP2A, B subunit, PR61 alpha isoform; protein phosphatase 2, regulatory subunit B', alpha isoform; protein phosphatase 2, regulatory subunit B (B56), alpha isoform; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform |
| UniProt Protein Name: | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform |
| UniProt Synonym Protein Names: | PP2A B subunit isoform B'-alpha; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform PR61-alpha; PR61alpha; PP2A B subunit isoform R5-alpha |
| Protein Family: | Serine/threonine-protein phosphatase |
| UniProt Gene Name: | PPP2R5A |
| UniProt Entry Name: | 2A5A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PPP2R5A antibody (CAB15706) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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