Anti-PPP2R3A Antibody (CAB17395)
- SKU:
- CAB17395
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PPP2R3A Antibody |
| 抗体コード: | CAB17395 |
| 抗体サイズ: | 50µL |
| 申し込み: | WB IHC |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant Protein of human PPP2R3A. |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant Protein of human PPP2R3A. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 5523 |
| Uniprot: | Q06190 |
| セルラーロケーション: | |
| 計算された分子量: | 48kDa/61kDa/130kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | PPP2R3, PR130, PR72, PPP2R3A |
| バックグラウンド: | This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | PPP2R3A: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit Chromosomal Location of Human Ortholog: 3q22.1 Cellular Component: protein phosphatase type 2A complex Molecular Function:protein binding; protein phosphatase type 2A regulator activity; calcium ion binding Biological Process: regulation of catalytic activity; positive regulation of protein catabolic process; eye photoreceptor cell differentiation; protein amino acid dephosphorylation; somatic muscle development |
| NCBI Summary: | This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Jun 2010] |
| UniProt Code: | Q06190 |
| NCBI GenInfo Identifier: | 543720 |
| NCBI Gene ID: | 5523 |
| NCBI Accession: | Q06190.1 |
| UniProt Related Accession: | Q06190 |
| Molecular Weight: | |
| NCBI Full Name: | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha |
| NCBI Synonym Full Names: | protein phosphatase 2 regulatory subunit B''alpha |
| NCBI Official Symbol: | PPP2R3A |
| NCBI Official Synonym Symbols: | PR72; PR130; PPP2R3 |
| NCBI Protein Information: | serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha |
| UniProt Protein Name: | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha |
| UniProt Synonym Protein Names: | PP2A subunit B isoform PR72/PR130; PP2A subunit B isoform R3 isoform; PP2A subunit B isoforms B''-PR72/PR130; PP2A subunit B isoforms B72/B130; Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B |
| UniProt Gene Name: | PPP2R3A |
| UniProt Entry Name: | P2R3A_HUMAN |
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