Anti-PPP2CB Antibody (CAB3122)
- SKU:
- CAB3122
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PPP2CB Antibody |
| 抗体コード: | CAB3122 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human PPP2CB (NP_001009552.1). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | LO2, 293T, Mouse brain, Mouse lung, Mouse spleen, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human PPP2CB (NP_001009552.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MDDK AFTK ELDQ WVEQ LNEC KQLN ENQV RTLC EKAK EILT KESN VQEV RCPV TVCG DVHG QFHD LMEL FRIG GKSP DTNY LFMG DYVD RGYY SVET VTLL VALK VRYP ERIT ILRG NHES RQIT QVYG FYDE CLRK YGNA NVWK YFTD LFDY LPLT ALVD GQIF CLHG GLSP SIDT LDHI RALD RLQE VPHE GPMC DLLW SDPD DRGG WGIS PRGA GYTF GQDI SETF NHAN GLTL VSRA HQLV MEGY NWCH DRNV VTIF SAPN YCYR CGNQ AAIM ELDD TLKY SFLQ FDPA PRRG EPHV TRRT PDYF L |
| 遺伝子ID: | 5516 |
| Uniprot: | P62714 |
| セルラーロケーション: | Chromosome, Cytoplasm, Nucleus, centromere, cytoskeleton, spindle pole |
| 計算された分子量: | 35kDa |
| 観察された分子量: | 36KDa |
| 同義語: | PPP2CB, PP2Abeta, PP2CB |
| バックグラウンド: | This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. |
| UniProt Protein Function: | PPP2CB: one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. |
| UniProt Protein Details: | Protein type:Protein phosphatase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; EC 3.1.3.16 Chromosomal Location of Human Ortholog: 8p12 Cellular Component: spindle pole; protein phosphatase type 2A complex; nucleus; cytosol; chromosome, pericentric region Molecular Function:protein C-terminus binding; protein binding; metal ion binding; protein serine/threonine phosphatase activity Biological Process: response to antibiotic; proteasomal ubiquitin-dependent protein catabolic process; apoptotic mitochondrial changes; fibroblast growth factor receptor signaling pathway; response to hydrogen peroxide; regulation of gene expression; negative regulation of Ras protein signal transduction; protein amino acid dephosphorylation |
| NCBI Summary: | This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010] |
| UniProt Code: | P62714 |
| NCBI GenInfo Identifier: | 50402236 |
| NCBI Gene ID: | 5516 |
| NCBI Accession: | P62714.1 |
| UniProt Secondary Accession: | P62714,P67775, P62715, P63330, P62716 P63331, |
| UniProt Related Accession: | P62714 |
| Molecular Weight: | 35kDa |
| NCBI Full Name: | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform |
| NCBI Synonym Full Names: | protein phosphatase 2 catalytic subunit beta |
| NCBI Official Symbol: | PPP2CB |
| NCBI Official Synonym Symbols: | PP2CB; PP2Abeta |
| NCBI Protein Information: | serine/threonine-protein phosphatase 2A catalytic subunit beta isoform |
| UniProt Protein Name: | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform |
| Protein Family: | PP2A regulatory |
| UniProt Gene Name: | PPP2CB |
| UniProt Entry Name: | PP2AB_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PPP2CB antibody (CAB3122) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded rat kidney using PPP2CB antibody (CAB3122) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human colon carcinoma using PPP2CB antibody (CAB3122) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse kidney using PPP2CB antibody (CAB3122) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of U-2 OS cells using PPP2CB antibody (CAB3122) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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