Anti-PPHLN1 Antibody (CAB17706)
- SKU:
- CAB17706
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-PPHLN1 Antibody |
| 抗体コード: | CAB17706 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 195-255 of human PPHLN1 (NP_958846.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, THP-1, Mouse testis, Rat testis, Rat spleen, Rat lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 195-255 of human PPHLN1 (NP_958846.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | KSDE SNLP EISE YEAG STAP LFTD QPEE PESN TTHG IELF EDSQ LTTR SKAI ASKT KEIE Q |
| 遺伝子ID: | 51535 |
| Uniprot: | Q8NEY8 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 53kDa |
 | Western blot - PPHLN1 Polyclonal Antibody (CAB17706) |
| 同義語: | CR, HSPC206, HSPC232, PPHLN1 |
| バックグラウンド: | The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | PPHLN1: Involved in epithelial differentiation and contributes to epidermal integrity and barrier formation. 7 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA-binding; Cytoskeletal Chromosomal Location of Human Ortholog: 12q12 Cellular Component: cytoplasm; Golgi apparatus; intracellular membrane-bound organelle; nucleoplasm Molecular Function:protein binding |
| NCBI Summary: | The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8NEY8 |
| NCBI GenInfo Identifier: | 46396942 |
| NCBI Gene ID: | 51535 |
| NCBI Accession: | Q8NEY8.2 |
| UniProt Secondary Accession: | Q8NEY8,Q86YT2, Q8IXN3, Q8TB09, Q96NB9, Q9NXL4, Q9P0P6 Q9P0R9, E9PAX8, |
| UniProt Related Accession: | Q8NEY8 |
| Molecular Weight: | 40,319 Da |
| NCBI Full Name: | Periphilin-1 |
| NCBI Synonym Full Names: | periphilin 1 |
| NCBI Official Symbol: | PPHLN1 |
| NCBI Official Synonym Symbols: | CR; HSPC206; HSPC232 |
| NCBI Protein Information: | periphilin-1 |
| UniProt Protein Name: | Periphilin-1 |
| UniProt Synonym Protein Names: | CDC7 expression repressor |
| Protein Family: | Periphilin |
| UniProt Gene Name: | PPHLN1 |
| UniProt Entry Name: | PPHLN_HUMAN |