Anti-PPFIA3 Antibody (CAB8714)
- SKU:
- CAB8714
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PPFIA3 Antibody |
| 抗体コード: | CAB8714 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 460-590 of human PPFIA3 (NP_003651.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | U-87MG, HeLa, 293T |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 460-590 of human PPFIA3 (NP_003651.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | NSLS EEIA NMKK LQDE LLLN KEQL LAEM ERMQ MEID QLRG RPPS SYSR SLPG SALE LRYS QAPT LPSG AHLD PYVA GSGR AGKR GRWS GVKE EPSK DWER SAPA GSIP PPFP GELD GSDE EEAE GMFG AEL |
| 遺伝子ID: | 8541 |
| Uniprot: | O75145 |
| セルラーロケーション: | Cell surface, Cytoplasm |
| 計算された分子量: | 132kDa/133kDa |
| 観察された分子量: | 133kDa |
| 同義語: | PPFIA3, LPNA3 |
| バックグラウンド: | The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. Liprin family protein has been shown to localize phosphatase LAR to cell focal adhesions and may be involved in the molecular organization of presynaptic active zones. |
| UniProt Protein Function: | May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. |
| NCBI Summary: | The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. Liprin family protein has been shown to localize phosphatase LAR to cell focal adhesions and may be involved in the molecular organization of presynaptic active zones. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O75145 |
| NCBI GenInfo Identifier: | 32189362 |
| NCBI Gene ID: | 8541 |
| NCBI Accession: | NP_003651.1 |
| UniProt Secondary Accession: | O75145,Q3MJA0, Q9H8B5, Q9UEW4, A8K142, |
| UniProt Related Accession: | O75145 |
| Molecular Weight: | 132,365 Da |
| NCBI Full Name: | liprin-alpha-3 |
| NCBI Synonym Full Names: | PTPRF interacting protein alpha 3 |
| NCBI Official Symbol: | PPFIA3 |
| NCBI Official Synonym Symbols: | LPNA3 |
| NCBI Protein Information: | liprin-alpha-3 |
| UniProt Protein Name: | Liprin-alpha-3 |
| UniProt Synonym Protein Names: | Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3; PTPRF-interacting protein alpha-3 |
| Protein Family: | Liprin |
| UniProt Gene Name: | PPFIA3 |
 | Western blot analysis of extracts of various cell lines, using PPFIA3 antibody (CAB8714) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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