Anti-PPARGC1B Antibody (CAB17258)
- SKU:
- CAB17258
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-PPARGC1B Antibody |
| 抗体コード: | CAB17258 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 850-950 of human PPARGC1B (NP_001166170.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse brain |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 850-950 of human PPARGC1B (NP_001166170.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SSRE LKRR FEVF GEIE ECEV LTRN RRGE KYGF ITYR CSEH AALS LTKG AALR KRNE PSFQ LSYG GLRH FCWP RYTD YDSN SEEA LPAS GKSK YEAM DFDS L |
| 遺伝子ID: | 133522 |
| Uniprot: | Q86YN6 |
| セルラーロケーション: | |
| 計算された分子量: | 106kDa/108kDa/110kDa/112kDa/113kDa |
| 観察された分子量: | 113kDa |
 | Western blot - PPARGC1B Rabbit pAb (CAB17258) |
| 同義語: | PPARGC1B, ERRL1, PERC, PGC-1(beta), PGC1B, PPARGC1B |
| バックグラウンド: | The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. |
| NCBI Summary: | The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] |
| UniProt Code: | Q86YN6 |
| NCBI GenInfo Identifier: | 289577090 |
| NCBI Gene ID: | 133522 |
| NCBI Accession: | NP_001166169.1 |
| UniProt Related Accession: | Q86YN6 |
| Molecular Weight: | 113kDa |
| NCBI Full Name: | peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform 2 |
| NCBI Synonym Full Names: | PPARG coactivator 1 beta |
| NCBI Official Symbol: | PPARGC1B |
| NCBI Official Synonym Symbols: | PERC; ERRL1; PGC1B; PGC-1(beta) |
| NCBI Protein Information: | peroxisome proliferator-activated receptor gamma coactivator 1-beta |
| UniProt Protein Name: | Peroxisome proliferator-activated receptor gamma coactivator 1-beta |
| UniProt Synonym Protein Names: | PGC-1-related estrogen receptor alpha coactivator |
| UniProt Gene Name: | PPARGC1B |
| UniProt Entry Name: | PRGC2_HUMAN |