Anti-PPA2 Antibody (CAB15819)
- SKU:
- CAB15819
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PPA2 Antibody |
| 抗体コード: | CAB15819 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 33-100 of human PPA2 (NP_008834.3). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-251MG, A-549, OVCAR3 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 33-100 of human PPA2 (NP_008834.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | ALYH TEER GQPC SQNY RLFF KNVT GHYI SPFH DIPL KVNS KEEN GIPM KKAR NDEY ENLF NMIV EIPR |
| 遺伝子ID: | 27068 |
| Uniprot: | Q9H2U2 |
| セルラーロケーション: | Mitochondrion |
| 計算された分子量: | 18kDa/25kDa/34kDa/37kDa/39kDa |
| 観察された分子量: | 38kDa |
| 同義語: | PPA2, HSPC124, SCFAI, SCFI, SID6-306 |
| バックグラウンド: | The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| UniProt Protein Function: | PPA2: is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Mitochondrial; Hydrolase; EC 3.6.1.1; Energy Metabolism - oxidative phosphorylation Chromosomal Location of Human Ortholog: 4q25 Cellular Component: mitochondrial matrix Molecular Function:inorganic diphosphatase activity; magnesium ion binding; protein serine/threonine phosphatase activity Biological Process: tRNA aminoacylation for protein translation; dephosphorylation; gene expression |
| NCBI Summary: | The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9H2U2 |
| NCBI GenInfo Identifier: | 77812678 |
| NCBI Gene ID: | 27068 |
| NCBI Accession: | NP_008834.3 |
| UniProt Secondary Accession: | Q9H2U2,Q4W5E9, Q6PG51, Q8TBW0, Q96E55, Q9H0T0, Q9NX37 Q9P033, Q9ULX0, B4DLP7, F8WDN9, I6L9B6, |
| UniProt Related Accession: | Q9H2U2 |
| Molecular Weight: | 25,992 Da |
| NCBI Full Name: | inorganic pyrophosphatase 2, mitochondrial isoform 2 |
| NCBI Synonym Full Names: | pyrophosphatase (inorganic) 2 |
| NCBI Official Symbol: | PPA2 |
| NCBI Official Synonym Symbols: | HSPC124; SID6-306 |
| NCBI Protein Information: | inorganic pyrophosphatase 2, mitochondrial |
| UniProt Protein Name: | Inorganic pyrophosphatase 2, mitochondrial |
| UniProt Synonym Protein Names: | Pyrophosphatase SID6-306; Pyrophosphate phospho-hydrolase 2; PPase 2 |
| Protein Family: | Soluble inorganic pyrophosphatase |
| UniProt Gene Name: | PPA2 |
| UniProt Entry Name: | IPYR2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PPA2 antibody (CAB15819) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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