Anti-POF1B Antibody (CAB17775)
- SKU:
- CAB17775
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
抗体名: | Anti-POF1B Antibody |
抗体コード: | CAB17775 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 330-560 of human POF1B (NP_079197.3). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Rat |
ポジティブサンプル: | Rat kidney |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 330-560 of human POF1B (NP_079197.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LVLS TFSN IREE LGHL QNDM TSLE NDKM RLEK DLSF KDTQ LKEY EELL ASVR ANNH QQQQ GLQD SSSK CQAL EENN LSLR HTLS DMEY RLKE LEYC KRNL EQEN QNLR MQVS ETCT GPML QAKM DEIG NHYT EMVK NLRM EKDR EICR LRSQ LNQY HKDV SKRE GSCS DFQF KLHE LTSL LEEK DSLI KRQS EELS KLRQ EIYS SHNQ PSTG GRTT ITTK KYRT QYPI LGL |
遺伝子ID: | 79983 |
Uniprot: | Q8WVV4 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | 85kDa |
同義語: | POF, POF2B, POF1B |
バックグラウンド: | Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called "POF1" and "POF2" have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined. [provided by RefSeq, Jan 2010] |
UniProt Protein Function: | Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton. May be involved in ovary development. |
NCBI Summary: | Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called "POF1" and "POF2" have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined. [provided by RefSeq, Jan 2010] |
UniProt Code: | Q8WVV4 |
NCBI GenInfo Identifier: | 332278224 |
NCBI Gene ID: | 79983 |
NCBI Accession: | Q8WVV4.3 |
UniProt Secondary Accession: | Q8WVV4,Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744 A8K2U5, |
UniProt Related Accession: | Q8WVV4 |
Molecular Weight: | 34,841 Da |
NCBI Full Name: | Protein POF1B |
NCBI Synonym Full Names: | premature ovarian failure, 1B |
NCBI Official Symbol: | POF1B |
NCBI Official Synonym Symbols: | POF; POF2B |
NCBI Protein Information: | protein POF1B |
UniProt Protein Name: | Protein POF1B |
UniProt Synonym Protein Names: | Premature ovarian failure protein 1B |
Protein Family: | Protein |
UniProt Gene Name: | POF1B |
UniProt Entry Name: | POF1B_HUMAN |