Anti-PODN Antibody (CAB14309)
- SKU:
- CAB14309
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PODN Antibody |
| 抗体コード: | CAB14309 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 67-210 of human PODN (NP_714914.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | U-87MG, Mouse eye |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 67-210 of human PODN (NP_714914.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LGPV LAVR APGF GRSG GHSL SPEE NEFA EEEP VLVL SPEE PGPG PAAV SCPR DCAC SQEG VVDC GGID LREF PGDL PEHT NHLS LQNN QLEK IYPE ELSR LHRL ETLN LQNN RLTS RGLP EKAF EHLT NLNY LYLA NNKL TLAP |
| 遺伝子ID: | 127435 |
| Uniprot: | Q7Z5L7 |
| セルラーロケーション: | Cytoplasm, Secreted, extracellular matrix, extracellular space |
| 計算された分子量: | 57kDa/68kDa/72kDa/74kDa |
| 観察された分子量: | 69kDa |
| 同義語: | PODN, PCAN, SLRR5A, podocan |
| バックグラウンド: | The protein encoded by this gene is a member of the small leucine-rich repeat protein family and contains an amino terminal CX3CXCX7C cysteine-rich cluster followed by a leucine-rich repeat domain. Studies suggest that this protein could function to inhibit smooth muscle cell proliferation and migration following arterial injury. |
| UniProt Protein Function: | PODN: Negatively regulates cell proliferation and cell migration. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class V subfamily. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 1p32.3 Cellular Component: cytoplasm; extracellular space Molecular Function:collagen binding; protein kinase inhibitor activity Biological Process: cytokine and chemokine mediated signaling pathway; negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of JAK-STAT cascade; negative regulation of protein kinase activity |
| NCBI Summary: | The protein encoded by this gene is a member of the small leucine-rich repeat protein family and contains an amino terminal CX3CXCX7C cysteine-rich cluster followed by a leucine-rich repeat domain. Studies suggest that this protein could function to inhibit smooth muscle cell proliferation and migration following arterial injury. [provided by RefSeq, Jul 2016] |
| UniProt Code: | Q7Z5L7 |
| NCBI GenInfo Identifier: | 118573110 |
| NCBI Gene ID: | 127435 |
| NCBI Accession: | Q7Z5L7.2 |
| UniProt Secondary Accession: | Q7Z5L7,Q5VVZ2, Q5VVZ3, Q6PIR3, Q6UXL8, Q8N641, B4DKN5 B4E373, |
| UniProt Related Accession: | Q7Z5L7 |
| Molecular Weight: | 57,896 Da |
| NCBI Full Name: | Podocan |
| NCBI Synonym Full Names: | podocan |
| NCBI Official Symbol: | PODN |
| NCBI Official Synonym Symbols: | PCAN; SLRR5A |
| NCBI Protein Information: | podocan |
| UniProt Protein Name: | Podocan |
| Protein Family: | Podocan |
| UniProt Gene Name: | PODN |
| UniProt Entry Name: | PODN_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PODN antibody (CAB14309) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
View AllClose